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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1wzy F29 Mitogen-activated protein kinase 1 2.7.11.24

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1wzy F29Mitogen-activated protein kinase 1 2.7.11.24 0.942
1tvo FRZMitogen-activated protein kinase 1 2.7.11.24 0.739
2xyu Q9GEphrin type-A receptor 4 2.7.10.1 0.676
1vjy 460TGF-beta receptor type-1 2.7.11.30 0.674
2wqb QQ1Angiopoietin-1 receptor 2.7.10.1 0.668
4fv9 E71Mitogen-activated protein kinase 1 2.7.11.24 0.659
4kba 1QMCasein kinase I isoform delta 2.7.11.1 0.656
1wbw LI4Mitogen-activated protein kinase 14 / 0.650
3erk SB4Mitogen-activated protein kinase 1 2.7.11.24 0.650