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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1wkh PPE [LysW]-aminoadipate semialdehyde transaminase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1wkh PPE[LysW]-aminoadipate semialdehyde transaminase / 1.042
4adc PLPSuccinylornithine transaminase 2.6.1.81 0.810
4jey PLPAcetylornithine/succinyldiaminopimelate aminotransferase 2.6.1.11 0.779
4zwm PLPOrnithine aminotransferase, mitochondrial, putative / 0.778
2ykv IK2Beta-transaminase / 0.752
3tfu PL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase 2.6.1.62 0.751
4aoa IK2Beta-phenylalanine transaminase 2.6.1 0.749
2hp2 KE4Glutamate-1-semialdehyde 2,1-aminomutase 5.4.3.8 0.721
1mlz PLPAdenosylmethionine-8-amino-7-oxononanoate aminotransferase 2.6.1.62 0.720
4jf1 PLPAcetylornithine/succinyldiaminopimelate aminotransferase 2.6.1.11 0.718
1cl2 PPGCystathionine beta-lyase MetC 4.4.1.8 0.688
4wxg 2BOSerine hydroxymethyltransferase / 0.686
1cq7 PY5Aspartate aminotransferase 2.6.1.1 0.684
4itx IN5Cystathionine beta-lyase MetC 4.4.1.8 0.683
4ba5 PXGProbable aminotransferase / 0.679
1arg PPDAspartate aminotransferase 2.6.1.1 0.672
2pb2 PLPAcetylornithine/succinyldiaminopimelate aminotransferase 2.6.1.11 0.666
1u08 PLPMethionine aminotransferase / 0.656
3tqx PLP2-amino-3-ketobutyrate coenzyme A ligase / 0.656
3ei8 PL5LL-diaminopimelate aminotransferase, chloroplastic / 0.655
2ycn P61Tyrosine phenol-lyase 4.1.99.2 0.651
1s07 PLPAdenosylmethionine-8-amino-7-oxononanoate aminotransferase 2.6.1.62 0.650