Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1trg CB3 Thymidylate synthase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1trg CB3Thymidylate synthase / 1.028
2aaz CB3Thymidylate synthase 2.1.1.45 0.900
2fto CB3Thymidylate synthase / 0.874
1tys DHFThymidylate synthase / 0.869
1kce CB3Thymidylate synthase / 0.859
2bbq PFGThymidylate synthase / 0.859
4gev CB3Thymidylate synthase / 0.856
4knz CB3Thymidylate synthase / 0.829
1zpr CB3Thymidylate synthase / 0.784
1aiq CB3Thymidylate synthase / 0.773
2tsc CB3Thymidylate synthase / 0.763
1tdu CB3Thymidylate synthase / 0.760
3bgx MEFThymidylate synthase / 0.739
1dna CB3Thymidylate synthase / 0.724
1nce CB3Thymidylate synthase / 0.724
3bhr THGThymidylate synthase / 0.710
1bq1 CB3Thymidylate synthase / 0.705
4eil CB3Bifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 0.705
2kce D16Thymidylate synthase / 0.692
1qzf CB3Bifunctional dihydrofolate reductase-thymidylate synthase / 0.691
4ez8 DHFThymidylate synthase 2.1.1.45 0.678
1kzj CB3Thymidylate synthase / 0.672
1ddu CB3Thymidylate synthase / 0.668
1an5 CB3Thymidylate synthase / 0.664
3k2h LYABifunctional dihydrofolate reductase-thymidylate synthase / 0.654