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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1thy UMP Thymidylate synthase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1thy UMPThymidylate synthase / 0.885
1tsy UMPThymidylate synthase / 0.705
1bid UMPThymidylate synthase / 0.697
2g8a UMPThymidylate synthase / 0.690
2g86 UMPThymidylate synthase / 0.688
1nje DCMThymidylate synthase / 0.684
1njc DCMThymidylate synthase / 0.683
1jmg UMPThymidylate synthase / 0.678
1f28 UMPThymidylate synthase 2.1.1.45 0.675
2g89 UMPThymidylate synthase / 0.674
1tsx UMPThymidylate synthase / 0.673
4iqq UMPThymidylate synthase / 0.663
1nja DCMThymidylate synthase / 0.662
1vzb UMPThymidylate synthase / 0.659
1jmh UMPThymidylate synthase / 0.656
1bp6 UMPThymidylate synthase / 0.653
1njd UMPThymidylate synthase / 0.653
4irr UMPThymidylate synthase / 0.653