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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1sg9 SAM Release factor glutamine methyltransferase 2.1.1.297

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1sg9 SAMRelease factor glutamine methyltransferase 2.1.1.297 0.880
1nv9 SAHRelease factor glutamine methyltransferase 2.1.1.297 0.762
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4e5i 0N9Polymerase acidic protein / 0.744
1vq1 SAMRelease factor glutamine methyltransferase 2.1.1.297 0.701
3dmh SAMProbable ribosomal RNA small subunit methyltransferase / 0.700
1nv8 SAMRelease factor glutamine methyltransferase 2.1.1.297 0.693
1nbh SAMGlycine N-methyltransferase 2.1.1.20 0.686
3b3f SAHHistone-arginine methyltransferase CARM1 / 0.682
2gs9 SAHUncharacterized protein / 0.681
1f3l SAHProtein arginine N-methyltransferase 3 / 0.680
3lcu SAH16S rRNA (guanine(1405)-N(7))-methyltransferase 2.1.1.179 0.680
3v97 SAHRibosomal RNA large subunit methyltransferase K/L 2.1.1.173 0.680
3dh0 SAMUncharacterized protein / 0.679
5icf SAH(S)-norcoclaurine 6-O-methyltransferase / 0.678
2y1x SAHHistone-arginine methyltransferase CARM1 / 0.677
3iei SAHLeucine carboxyl methyltransferase 1 2.1.1.233 0.677
4hh4 SAHCcbJ / 0.677
2bzg SAHThiopurine S-methyltransferase 2.1.1.67 0.674
3kpj SAHPhenylethanolamine N-methyltransferase 2.1.1.28 0.673
2v74 SAHHistone-arginine methyltransferase CARM1 / 0.668
3fri SAH16S rRNA methylase / 0.668
4azw SAMO-antigen chain terminator bifunctional methyltransferase/kinase WbdD / 0.667
3cjt SAHRibosomal protein L11 methyltransferase 2.1.1 0.664
4gek GEKCarboxy-S-adenosyl-L-methionine synthase / 0.662
4e5f 0N7Polymerase acidic protein / 0.660
3egv SAHRibosomal protein L11 methyltransferase 2.1.1 0.658
3cjq SAHRibosomal protein L11 methyltransferase 2.1.1 0.657
3dmg SAHProbable ribosomal RNA small subunit methyltransferase / 0.657
1rje SAHLeucine carboxyl methyltransferase 1 2.1.1.233 0.656
2zzn SAMtRNA (guanine(37)-N1)-methyltransferase Trm5b 2.1.1.228 0.656
1rjd SAMLeucine carboxyl methyltransferase 1 2.1.1.233 0.654
3reo SAH(Iso)eugenol O-methyltransferase 2.1.1.146 0.653
2nxe SAMRibosomal protein L11 methyltransferase 2.1.1 0.652
5f2k SAHUncharacterized protein / 0.650