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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1s20 NAD 2,3-diketo-L-gulonate reductase 1.1.1.130

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1s20 NAD2,3-diketo-L-gulonate reductase 1.1.1.130 1.028
1z2i NADPutative malate dehydrogenase / 0.737
4h8a NAIUreidoglycolate dehydrogenase (NAD(+)) 1.1.1.350 0.678
2x06 NADL-sulfolactate dehydrogenase / 0.672
2g8y NADHydroxycarboxylate dehydrogenase B / 0.661
2cwf NDPDelta(1)-pyrroline-2-carboxylate/Delta(1)-piperideine-2-carboxylate reductase / 0.660
4nfs NAJAlcohol dehydrogenase E chain 1.1.1.1 0.658
2h29 DNDProbable nicotinate-nucleotide adenylyltransferase / 0.652
1v9n NDPMalate dehydrogenase 1.1.1.37 0.651