Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1r4l XX5 Angiotensin-converting enzyme 2 3.4.17.23

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1r4l XX5Angiotensin-converting enzyme 2 3.4.17.23 1.121
1uze EALAngiotensin-converting enzyme 3.2.1 0.692
4isu IKMGlutamate receptor 2 / 0.674
1u5a BIKL-lactate dehydrogenase 1.1.1.27 0.663
3zhv TDWMultifunctional 2-oxoglutarate metabolism enzyme 1.2.4.2 0.662
1u4g HPIElastase 3.4.24.26 0.660
4m6l 21VDihydrofolate reductase 1.5.1.3 0.656
1hfq MOTDihydrofolate reductase 1.5.1.3 0.652
4m6k FOLDihydrofolate reductase 1.5.1.3 0.650