Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1r2j FAD FkbI

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1r2j FADFkbI / 1.113
3mpi FADGlutaryl-CoA dehydrogenase 1.3.99.32 0.851
4m9a FDAAcyl-CoA dehydrogenase / 0.834
2dvl FADAcyl-CoA dehydrogenase / 0.819
1jqi FADShort-chain specific acyl-CoA dehydrogenase, mitochondrial / 0.809
3mdd FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.806
5af7 FADAcyl-CoA dehydrogenase / 0.802
1rx0 FADIsobutyryl-CoA dehydrogenase, mitochondrial 1.3.99 0.801
3sf6 FDAGlutaryl-CoA dehydrogenase / 0.794
1buc FADAcyl-CoA dehydrogenase, short-chain specific 1.3.8.1 0.791
5jsc FADPutative acyl-CoA dehydrogenase / 0.779
4p13 FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.775
3pfd FDAAcyl-CoA dehydrogenase FadE25 / 0.772
1egd FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.759
5ahs FADAcyl-CoA dehydrogenase / 0.759
3oib FDAPutative acyl-CoA dehydrogenase / 0.758
3nf4 FADAcyl-CoA dehydrogenase domain-containing protein / 0.757
3owa FADAcyl-CoA dehydrogenase / 0.756
2vig FADShort-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.1 0.751
2ix5 FADAcyl-coenzyme A oxidase 4, peroxisomal 1.3.3.6 0.745
2a1t FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.741
1ege FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.736
3mpj FADGlutaryl-CoA dehydrogenase 1.3.99.32 0.729
1udy FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.718
2eba FADPutative glutaryl-CoA dehydrogenase / 0.715
2pg0 FADAcyl-CoA dehydrogenase / 0.714
4x28 FDAAcyl-CoA dehydrogenase FadE26 / 0.708
4x28 FDAAcyl-CoA dehydrogenase FadE27 / 0.708
1t9g FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial 1.3.8.7 0.696
2fon FADAcyl-coenzyme A oxidase / 0.689
1siq FADGlutaryl-CoA dehydrogenase, mitochondrial 1.3.8.6 0.687
3mkh FADNitroalkane oxidase / 0.687
1tj1 FADBifunctional protein PutA 1.5.5.2 0.685
3hji FADVivid PAS protein VVD / 0.685
4hj6 FMNLOV protein / 0.683
1n4w FADCholesterol oxidase 1.1.3.6 0.682
4xwr FADCholesterol oxidase 1.1.3.6 0.682
4xxg FADCholesterol oxidase 1.1.3.6 0.682
4yus FMNFamily 3 adenylate cyclase / 0.676
3hgo FMN12-oxophytodienoate reductase 3 1.3.1.42 0.675
4utl FNRXenobiotic reductase / 0.673
4zoh FADPutative oxidoreductase FAD-binding subunit / 0.670
1mxt FAECholesterol oxidase 1.1.3.6 0.668
1n1p FADCholesterol oxidase 1.1.3.6 0.668
4o8a FADBifunctional protein PutA 1.2.1.88 0.668
3gfz FMNUncharacterized protein / 0.667
4ef8 FMNDihydroorotate dehydrogenase (fumarate) / 0.667
4y9l FADAcyl-CoA dehydrogenase family member 11 / 0.667
1gg5 FADNAD(P)H dehydrogenase [quinone] 1 1.6.5.2 0.666
3r7k FDAProbable acyl CoA dehydrogenase / 0.666
1cbo FADCholesterol oxidase 1.1.3.6 0.665
1n4u FAECholesterol oxidase 1.1.3.6 0.665
2gew FADCholesterol oxidase 1.1.3.6 0.665
4u2t FADCholesterol oxidase 1.1.3.6 0.665
3b6d FAECholesterol oxidase 1.1.3.6 0.664
3c3n FMNDihydroorotate dehydrogenase (fumarate) 1.3.98.1 0.664
1b8s FADCholesterol oxidase 1.1.3.6 0.663
1n4v FADCholesterol oxidase 1.1.3.6 0.663
3cox FADCholesterol oxidase 1.1.3.6 0.663
3qe2 FMNNADPH--cytochrome P450 reductase / 0.663
4hia FMNLOV protein / 0.663
4r38 RBFBlue-light-activated histidine kinase 2 2.7.13.3 0.663
2fzm FADBifunctional protein PutA 1.5.5.2 0.662
3gyi FADCholesterol oxidase 1.1.3.6 0.662
4u2s FDACholesterol oxidase 1.1.3.6 0.662
1jue FMNDihydroorotate dehydrogenase A (fumarate) 1.3.98.1 0.661
1z44 FMNNADPH dehydrogenase / 0.661
2q3o FMN12-oxophytodienoate reductase 3 1.3.1.42 0.661
1ijh FADCholesterol oxidase 1.1.3.6 0.660
3cnj FADCholesterol oxidase 1.1.3.6 0.660
3l5l FMNXenobiotic reductase / 0.660
1cc2 FADCholesterol oxidase 1.1.3.6 0.658
2gmh FADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial 1.5.5.1 0.658
3djl FADPutative acyl-CoA dehydrogenase AidB 1.3.99 0.658
4ef9 FMNDihydroorotate dehydrogenase (fumarate) / 0.657
4udq FAD5-(hydroxymethyl)furfural oxidase / 0.657
4jn9 FADDepH / 0.656
5eb5 FAD(R)-mandelonitrile lyase 1 4.1.2.10 0.656
4j2w FADKynurenine 3-monooxygenase / 0.654
4udr FAD5-(hydroxymethyl)furfural oxidase / 0.654
4nmb FADBifunctional protein PutA / 0.653
4utk FNRXenobiotic reductase / 0.653
1ju2 FAD(R)-mandelonitrile lyase 2 4.1.2.10 0.652
1zwl FMNNAD(P)H dehydrogenase (quinone) 1.6.5.2 0.652
3gyj FADCholesterol oxidase 1.1.3.6 0.652
4wzh FMNDihydroorotate dehydrogenase (fumarate) / 0.651
4rek FADCholesterol oxidase 1.1.3.6 0.650
4tmc FMNOld yellow enzyme / 0.650