Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1qk3 5GP Hypoxanthine-guanine-xanthine phosphoribosyltransferase 2.4.2.22

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1qk3 5GPHypoxanthine-guanine-xanthine phosphoribosyltransferase 2.4.2.22 0.948
2fxv 5GPXanthine phosphoribosyltransferase 2.4.2.22 0.675
5iqf GDPBifunctional AAC/APH 2.3.1 0.675
3gep 24HHypoxanthine-guanine phosphoribosyltransferase 2.4.2.8 0.666
4dtb GMPAPH(2'')-Id / 0.662
1hmp 5GPHypoxanthine-guanine phosphoribosyltransferase 2.4.2.8 0.661
1jsz NDMCap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2.1.1.57 0.661
3ggj 25HHypoxanthine-guanine phosphoribosyltransferase 2.4.2.8 0.660
3dyl PCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.652
3dy8 5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.651