Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1pmu 9HP Mitogen-activated protein kinase 10 2.7.11.24

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1pmu 9HPMitogen-activated protein kinase 10 2.7.11.24 1.071
3tiz 3TICyclin-dependent kinase 2 2.7.11.22 0.739
4mf0 29ZTyrosine-protein kinase ITK/TSK 2.7.10.2 0.670
2gnl H52cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.669
1pmv 537Mitogen-activated protein kinase 10 2.7.11.24 0.662
1ajv NMBGag-Pol polyprotein 3.4.23.16 0.657
4mbl 26LSerine/threonine-protein kinase pim-1 2.7.11.1 0.654
2xm9 LWHSerine/threonine-protein kinase Chk2 2.7.11.1 0.651