sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1pdh | FAS | p-hydroxybenzoate hydroxylase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 1.343 | |
| 1k0j | FAD | p-hydroxybenzoate hydroxylase | / | 0.975 | |
| 1k0l | FAD | p-hydroxybenzoate hydroxylase | / | 0.966 | |
| 1d7l | RFL | p-hydroxybenzoate hydroxylase | / | 0.937 | |
| 2xdo | FAD | TetX family tetracycline inactivation enzyme | / | 0.896 | |
| 3oz2 | FAD | Digeranylgeranylglycerophospholipid reductase | / | 0.867 | |
| 4k5r | FAD | Oxygenase | / | 0.867 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.863 | |
| 5eow | FAD | 6-hydroxynicotinate 3-monooxygenase | 1.14.13.114 | 0.863 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.851 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.827 | |
| 3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.825 | |
| 1ges | FAD | Glutathione reductase | 1.8.1.7 | 0.823 | |
| 4j2w | FAD | Kynurenine 3-monooxygenase | / | 0.823 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.821 | |
| 4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.815 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.813 | |
| 2yqu | FAD | Dihydrolipoyl dehydrogenase | / | 0.813 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.806 | |
| 3fbs | FAD | Oxidoreductase | / | 0.799 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.797 | |
| 2eq6 | FAD | Dihydrolipoyl dehydrogenase | / | 0.795 | |
| 3ish | FAD | Thioredoxin reductase | 1.8.1.9 | 0.795 | |
| 3lzw | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.795 | |
| 1gth | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.794 | |
| 1ger | FAD | Glutathione reductase | 1.8.1.7 | 0.792 | |
| 4j34 | FAD | Kynurenine 3-monooxygenase | / | 0.783 | |
| 5buk | FAD | FADH2-dependent halogenase | / | 0.783 | |
| 4fx9 | FAD | Coenzyme A disulfide reductase | 1.8.1.14 | 0.782 | |
| 4j33 | FAD | Kynurenine 3-monooxygenase | / | 0.781 | |
| 3rnm | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.779 | |
| 1gte | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.778 | |
| 2f5z | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.777 | |
| 4bjz | FAD | Probable salicylate monooxygenase | / | 0.774 | |
| 3icr | FAD | Coenzyme A disulfide reductase | / | 0.773 | |
| 1mo9 | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.772 | |
| 2qa1 | FAD | PgaE | / | 0.767 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.767 | |
| 1e6e | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.766 | |
| 3rha | FDA | Putrescine oxidase | / | 0.766 | |
| 4icy | FAD | PgaE | / | 0.766 | |
| 4jn9 | FAD | DepH | / | 0.765 | |
| 4nte | FAD | DepH | / | 0.765 | |
| 1geu | FAD | Glutathione reductase | 1.8.1.7 | 0.764 | |
| 3oc4 | FAD | Oxidoreductase, pyridine nucleotide-disulfide family | / | 0.763 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.762 | |
| 3rp8 | FAD | FAD-dependent urate hydroxylase | / | 0.762 | |
| 4j36 | FAD | Kynurenine 3-monooxygenase | / | 0.762 | |
| 2eq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.758 | |
| 3cge | FAD | Coenzyme A disulfide reductase | / | 0.757 | |
| 3ics | FAD | Coenzyme A disulfide reductase | / | 0.757 | |
| 4nzh | FAD | L-ornithine N(5)-monooxygenase | / | 0.756 | |
| 4tlz | FAD | KtzI | / | 0.754 | |
| 2eq8 | FAD | Dihydrolipoyl dehydrogenase | / | 0.752 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.752 | |
| 3p9u | FAD | TetX family tetracycline inactivation enzyme | / | 0.752 | |
| 1bwc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.751 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.751 | |
| 1fl2 | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.750 | |
| 3atq | FDA | Conserved Archaeal protein | / | 0.750 | |
| 2c3c | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.749 | |
| 4em4 | FAD | Coenzyme A disulfide reductase | / | 0.748 | |
| 4gcm | FAD | Thioredoxin reductase | 1.8.1.9 | 0.748 | |
| 4guv | FAD | TetX family tetracycline inactivation enzyme | / | 0.748 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.747 | |
| 1get | FAD | Glutathione reductase | 1.8.1.7 | 0.745 | |
| 4jdr | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.745 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.744 | |
| 2q0l | FAD | Thioredoxin reductase | 1.8.1.9 | 0.744 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.743 | |
| 1zmd | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.743 | |
| 2v6o | FAD | Thioredoxin glutathione reductase | / | 0.743 | |
| 2c3d | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.742 | |
| 3grs | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.742 | |
| 3urh | FAD | Dihydrolipoyl dehydrogenase | / | 0.741 | |
| 4eqw | FAD | Coenzyme A disulfide reductase | / | 0.740 | |
| 1h7w | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.739 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.739 | |
| 4tlx | FDA | KtzI | / | 0.739 | |
| 4cnk | FAD | L-amino acid oxidase | / | 0.737 | |
| 4j56 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.737 | |
| 4ntd | FAD | Thioredoxin reductase | / | 0.736 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.735 | |
| 4z2t | FAD | 2-hydroxybiphenyl-3-monooxygenase | / | 0.735 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.733 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.733 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.732 | |
| 5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.732 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.731 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.731 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.731 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.730 | |
| 4x4j | FAD | Putative oxygenase | / | 0.730 | |
| 3alj | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.729 | |
| 1nhr | FAD | NADH peroxidase | 1.11.1.1 | 0.728 | |
| 3all | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.728 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.728 | |
| 4fk1 | FAD | Putative thioredoxin reductase | / | 0.728 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.728 | |
| 4gus | FAD | Lysine-specific histone demethylase 1B | 1 | 0.727 | |
| 3ef6 | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.726 | |
| 3ihg | FAD | Aklavinone 12-hydroxylase RdmE | / | 0.726 | |
| 4jq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.726 | |
| 2bab | FAD | Putative aminooxidase | / | 0.725 | |
| 4b69 | FAD | L-ornithine N(5)-monooxygenase | / | 0.723 | |
| 5dbj | FAD | FADH2-dependent halogenase PltA | / | 0.723 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.722 | |
| 5cku | FAD | L-ornithine N(5)-monooxygenase | / | 0.722 | |
| 2dki | FAD | 3-hydroxybenzoate 4-monooxygenase | 1.14.13.23 | 0.721 | |
| 2zbw | FAD | Ferredoxin--NADP reductase | / | 0.721 | |
| 3dgz | FAD | Thioredoxin reductase 2, mitochondrial | 1.8.1.9 | 0.721 | |
| 2rgj | FAD | Flavin-containing monooxygenase | / | 0.719 | |
| 3cgb | FAD | Coenzyme A disulfide reductase | / | 0.719 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.718 | |
| 4mo2 | FAD | UDP-galactopyranose mutase | / | 0.717 | |
| 1nhs | FAD | NADH peroxidase | 1.11.1.1 | 0.716 | |
| 2jb1 | FAD | L-amino acid oxidase | / | 0.716 | |
| 2npx | FAD | NADH peroxidase | 1.11.1.1 | 0.716 | |
| 3nix | FAD | Flavoprotein/dehydrogenase | / | 0.715 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.715 | |
| 2rab | FAD | Glutathione amide reductase | / | 0.713 | |
| 4xwz | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.713 | |
| 1jki | NAI | Inositol-3-phosphate synthase | 5.5.1.4 | 0.712 | |
| 1k4q | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.712 | |
| 2b9y | FAD | Putative aminooxidase | / | 0.711 | |
| 3cgd | FAD | Coenzyme A disulfide reductase | / | 0.711 | |
| 2hqm | FAD | Glutathione reductase | 1.8.1.7 | 0.709 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.709 | |
| 4b63 | FAD | L-ornithine N(5)-monooxygenase | / | 0.709 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.708 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.708 | |
| 3uox | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.708 | |
| 4tm1 | FDA | KtzI | / | 0.708 | |
| 4ykg | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.708 | |
| 2vqb | FAD | Putative flavin-containing monooxygenase | / | 0.707 | |
| 2q0k | FAD | Thioredoxin reductase | 1.8.1.9 | 0.706 | |
| 3cgc | FAD | Coenzyme A disulfide reductase | / | 0.706 | |
| 3ntd | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.706 | |
| 4eqs | FAD | Coenzyme A disulfide reductase | / | 0.706 | |
| 2r9z | FAD | Glutathione amide reductase | / | 0.705 | |
| 3c4a | FAD | Protodeoxyviolaceinate monooxygenase | 1 | 0.704 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.704 | |
| 2wow | FAD | Trypanothione reductase | / | 0.702 | |
| 4bk2 | FAD | Probable salicylate monooxygenase | / | 0.702 | |
| 2a8x | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.700 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.699 | |
| 4dna | FAD | Probable glutathione reductase | / | 0.699 | |
| 4em3 | FAD | Coenzyme A disulfide reductase | / | 0.699 | |
| 1gv4 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.698 | |
| 4m52 | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.696 | |
| 1gra | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.695 | |
| 1npx | FAD | NADH peroxidase | 1.11.1.1 | 0.695 | |
| 1zmc | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.695 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.695 | |
| 3fg2 | FAD | Putative rubredoxin reductase | / | 0.694 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.694 | |
| 3we0 | FAD | Lysine 2-monooxygenase | / | 0.694 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.693 | |
| 4tm0 | FAD | KtzI | / | 0.693 | |
| 1dnc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.692 | |
| 2tmd | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.692 | |
| 3kve | FAD | L-amino-acid oxidase | / | 0.692 | |
| 4h4p | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.692 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.691 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.691 | |
| 1zx9 | FAD | Mercuric reductase | 1.16.1.1 | 0.690 | |
| 5g3t | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.690 | |
| 4eqx | FAD | Coenzyme A disulfide reductase | / | 0.689 | |
| 1nhp | FAD | NADH peroxidase | 1.11.1.1 | 0.687 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.687 | |
| 4usr | FAD | Monooxygenase | / | 0.687 | |
| 2fjb | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.686 | |
| 2yr4 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.686 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.686 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.686 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.685 | |
| 4eqr | FAD | Coenzyme A disulfide reductase | / | 0.685 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.683 | |
| 3ka7 | FAD | Putative oxidoreductase | / | 0.683 | |
| 4h4z | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.683 | |
| 1fec | FAD | Trypanothione reductase | 1.8.1.12 | 0.682 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.682 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.682 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.681 | |
| 5fs9 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.681 | |
| 1wam | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.680 | |
| 1zmd | NAI | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.680 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.680 | |
| 4ntc | FAD | Thioredoxin reductase gliT | / | 0.680 | |
| 1yqz | FAD | Coenzyme A disulfide reductase | / | 0.679 | |
| 2gr0 | FAD | Ferredoxin reductase | / | 0.679 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.679 | |
| 1jeh | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.678 | |
| 2gr3 | FAD | Ferredoxin reductase | / | 0.678 | |
| 3lxd | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.678 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.678 | |
| 4ech | FAD | Polyamine oxidase FMS1 | / | 0.678 | |
| 4emw | FAD | Coenzyme A disulfide reductase | / | 0.678 | |
| 4h4t | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.678 | |
| 4h4v | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.678 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.678 | |
| 4tm4 | FDA | KtzI | / | 0.678 | |
| 1o94 | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.677 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.677 | |
| 4h4r | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.677 | |
| 4h4x | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.677 | |
| 4j31 | FAD | Kynurenine 3-monooxygenase | / | 0.677 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.676 | |
| 2jb2 | FAD | L-amino acid oxidase | / | 0.676 | |
| 4mo2 | FDA | UDP-galactopyranose mutase | / | 0.676 | |
| 1djn | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.675 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.675 | |
| 2xyo | FAD | TetX family tetracycline inactivation enzyme | / | 0.675 | |
| 2ylw | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.675 | |
| 3atr | FDA | Conserved Archaeal protein | / | 0.675 | |
| 2yg6 | FAD | Putrescine oxidase | / | 0.674 | |
| 3gwd | FAD | Cyclohexanone monooxygenase | / | 0.674 | |
| 1tyt | FAD | Trypanothione reductase | 1.8.1.12 | 0.673 | |
| 2iw5 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.673 | |
| 4gr1 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.673 | |
| 4h2p | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.673 | |
| 4txi | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.673 | |
| 1m6i | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.672 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.672 | |
| 4tm3 | FAD | KtzI | / | 0.672 | |
| 5ccx | SAH | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A | 2.1.1.220 | 0.672 | |
| 2zzc | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.671 | |
| 3v76 | FDA | Uncharacterized protein | / | 0.671 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.670 | |
| 1jnz | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.670 | |
| 2bi8 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.670 | |
| 3ept | FDA | Putative FAD-monooxygenase | / | 0.670 | |
| 1lpf | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.669 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.669 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.669 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.669 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.668 | |
| 1trb | FAD | Thioredoxin reductase | 1.8.1.9 | 0.668 | |
| 3l8k | ADP | Dihydrolipoamide dehydrogenase (PdhD-3) | / | 0.668 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.668 | |
| 4opt | FDA | Conserved Archaeal protein | / | 0.668 | |
| 5fs8 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.668 | |
| 1p1h | NAD | Inositol-3-phosphate synthase | 5.5.1.4 | 0.667 | |
| 1tde | FAD | Thioredoxin reductase | 1.8.1.9 | 0.667 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.667 | |
| 4nec | SAH | Putative SAM-dependent methyltransferase | / | 0.667 | |
| 1gxf | FAD | Trypanothione reductase | 1.8.1.12 | 0.666 | |
| 2q3e | NAI | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.666 | |
| 4opl | FDA | Conserved Archaeal protein | / | 0.666 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.665 | |
| 2nvk | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.665 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.665 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.665 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.665 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.665 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.665 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.664 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.664 | |
| 2rgh | FAD | Alpha-Glycerophosphate Oxidase | / | 0.664 | |
| 3dk4 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.664 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.663 | |
| 2yg7 | FAD | Putrescine oxidase | / | 0.662 | |
| 2yls | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.662 | |
| 4bk3 | FAD | Probable salicylate monooxygenase | / | 0.662 | |
| 4opd | FDA | Conserved Archaeal protein | / | 0.662 | |
| 2b9x | FAD | Putative aminooxidase | / | 0.661 | |
| 2tpr | FAD | Trypanothione reductase | 1.8.1.12 | 0.661 | |
| 3lzx | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.661 | |
| 3nlc | FAD | Uncharacterized protein | / | 0.661 | |
| 3sqp | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.661 | |
| 4emi | NAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.661 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.661 | |
| 4opc | FDA | Conserved Archaeal protein | / | 0.661 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.661 | |
| 1nhq | FAD | NADH peroxidase | 1.11.1.1 | 0.660 | |
| 3dk9 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.660 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.660 | |
| 4b66 | FAD | L-ornithine N(5)-monooxygenase | / | 0.660 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.660 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.659 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.659 | |
| 1grb | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.658 | |
| 1lld | NAD | L-lactate dehydrogenase 2 | 1.1.1.27 | 0.658 | |
| 3d64 | NAD | Adenosylhomocysteinase | / | 0.658 | |
| 4j57 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.658 | |
| 2cul | FAD | GidA-related protein | / | 0.657 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.657 | |
| 2qae | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.657 | |
| 3m0o | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.657 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.656 | |
| 1grh | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.655 | |
| 2eq7 | FAD | Dihydrolipoyl dehydrogenase | / | 0.655 | |
| 2o06 | MTA | Spermidine synthase | 2.5.1.16 | 0.655 | |
| 2wba | FAD | Trypanothione reductase | 1.8.1.12 | 0.655 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.655 | |
| 3int | FDA | UDP-galactopyranose mutase | 5.4.99.9 | 0.655 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.655 | |
| 4bv6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.655 | |
| 4d04 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.655 | |
| 1f3p | FAD | Ferredoxin reductase | / | 0.654 | |
| 1gre | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.654 | |
| 1gsn | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.654 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.654 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.654 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.654 | |
| 4jy2 | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.654 | |
| 4pyo | SAH | Catechol O-methyltransferase | 2.1.1.6 | 0.654 | |
| 1bzl | FAD | Trypanothione reductase | 1.8.1.12 | 0.653 | |
| 2q28 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.653 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.653 | |
| 3axb | FAD | Putative oxidoreductase | / | 0.652 | |
| 4cnj | FAD | L-amino acid oxidase | / | 0.652 | |
| 1ebd | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.651 | |
| 2yr5 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.651 | |
| 3lad | FAD | Dihydrolipoyl dehydrogenase | / | 0.650 | |
| 4lii | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.650 | |
| 4pyn | SAH | Catechol O-methyltransferase | 2.1.1.6 | 0.650 |