Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1pd9 CO4 Dihydrofolate reductase 1.5.1.3

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1pd9 CO4Dihydrofolate reductase 1.5.1.3 0.987
1pd8 CO4Dihydrofolate reductase 1.5.1.3 0.836
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4e5i 0N9Polymerase acidic protein / 0.744
1s3u TQDDihydrofolate reductase 1.5.1.3 0.740
1u71 MXADihydrofolate reductase 1.5.1.3 0.711
1s3v TQDDihydrofolate reductase 1.5.1.3 0.703
4m2x TMQDihydrofolate reductase 1.5.1.3 0.702
4p66 MTXDihydrofolate reductase / 0.680
1kms LIHDihydrofolate reductase 1.5.1.3 0.671
4qi9 MTXDihydrofolate reductase / 0.668
1hfq MOTDihydrofolate reductase 1.5.1.3 0.667
1dls MTXDihydrofolate reductase 1.5.1.3 0.665
3d80 Q22Dihydrofolate reductase 1.5.1.3 0.660
4e5f 0N7Polymerase acidic protein / 0.660
3dau MTXDihydrofolate reductase 1.5.1.3 0.659
3ql3 FOLDihydrofolate reductase 1.5.1.3 0.659
1mvs DTMDihydrofolate reductase 1.5.1.3 0.657
1dra MTXDihydrofolate reductase 1.5.1.3 0.654
1rh3 MTXDihydrofolate reductase 1.5.1.3 0.653
2w3w VG9Dihydrofolate reductase / 0.653
1mvt DTMDihydrofolate reductase 1.5.1.3 0.651