sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 1.324 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 1.126 | |
| 2cnt | COA | Ribosomal-protein-alanine acetyltransferase | / | 0.864 | |
| 2fiw | ACO | GCN5-related N-acetyltransferase:Aminotransferase, class-II | / | 0.849 | |
| 4jwp | ACO | GCN5-related N-acetyltransferase | / | 0.829 | |
| 4kvx | ACO | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.828 | |
| 3te4 | ACO | Dopamine N-acetyltransferase | / | 0.824 | |
| 3fbu | COA | Acetyltransferase, GNAT family | / | 0.820 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.812 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.812 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.811 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.811 | |
| 1bob | ACO | Histone acetyltransferase type B catalytic subunit | / | 0.798 | |
| 2r8v | ACO | Amino-acid acetyltransferase | / | 0.796 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.796 | |
| 5kgj | ACO | Predicted acetyltransferase | / | 0.793 | |
| 4r3k | COA | N-alpha-acetyltransferase | 2.3.1 | 0.784 | |
| 1qsn | COA | HAT A1 | / | 0.782 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.779 | |
| 2x7b | COA | N-alpha-acetyltransferase | 2.3.1 | 0.778 | |
| 1wwz | ACO | Uncharacterized protein | / | 0.776 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.774 | |
| 3f8k | COA | Uncharacterized protein | / | 0.772 | |
| 1pua | COA | HAT A1 | / | 0.764 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.762 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.761 | |
| 3r96 | ACO | MccE protein | / | 0.754 | |
| 3r1k | COA | N-acetyltransferase Eis | / | 0.753 | |
| 1qsm | ACO | Histone acetyltransferase HPA2 | / | 0.752 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.752 | |
| 2bei | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.748 | |
| 2q4v | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.746 | |
| 3r95 | ACO | MccE protein | / | 0.740 | |
| 3pgp | ACO | Uncharacterized protein | / | 0.739 | |
| 2vbq | BSJ | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.737 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.737 | |
| 1ghe | ACO | Acetyltransferase | 2.3.1 | 0.736 | |
| 3d2m | COA | Amino-acid acetyltransferase | / | 0.736 | |
| 1l0c | COT | Serotonin N-acetyltransferase | / | 0.733 | |
| 1kuv | CA5 | Serotonin N-acetyltransferase | / | 0.732 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.728 | |
| 4xpd | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.728 | |
| 5kf2 | COA | Predicted acetyltransferase | / | 0.725 | |
| 3exn | ACO | Probable acetyltransferase | / | 0.724 | |
| 1kuy | COT | Serotonin N-acetyltransferase | / | 0.721 | |
| 1cjw | COT | Serotonin N-acetyltransferase | / | 0.720 | |
| 4r87 | COA | Spermidine N(1)-acetyltransferase | / | 0.720 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.719 | |
| 3cz7 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.712 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.707 | |
| 1kux | CA3 | Serotonin N-acetyltransferase | / | 0.703 | |
| 4u9v | ACO | N-alpha-acetyltransferase 40 | 2.3.1 | 0.699 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.698 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.698 | |
| 1pu9 | COA | HAT A1 | / | 0.697 | |
| 2ft0 | ACO | dTDP-fucosamine acetyltransferase | / | 0.697 | |
| 1s7n | COA | Acetyl transferase | / | 0.695 | |
| 2zw4 | COA | Bleomycin acetyltransferase | / | 0.695 | |
| 4qvt | ACO | Acetyltransferase YpeA | 2.3.1 | 0.694 | |
| 5ag7 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.689 | |
| 2zfn | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.688 | |
| 2vzz | SCA | Putative succinyl-CoA transferase Rv0802c | 2.8.3 | 0.687 | |
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.685 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.681 | |
| 2vqy | ACO | AAC(6')-Ib | / | 0.678 | |
| 3bj7 | COA | Diamine acetyltransferase 1 | / | 0.678 | |
| 4kub | COA | Uncharacterized protein | / | 0.678 | |
| 3dr8 | ACO | L-methionine sulfoximine/L-methionine sulfone acetyltransferase | / | 0.677 | |
| 5h86 | BCO | Histone acetyltransferase KAT2A | 2.3.1.48 | 0.674 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.669 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.664 | |
| 5kf1 | ACO | Predicted acetyltransferase | / | 0.663 | |
| 1ib1 | COT | Serotonin N-acetyltransferase | / | 0.659 | |
| 5ag4 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.657 | |
| 3k9u | ACO | Spermidine N(1)-acetyltransferase | / | 0.652 | |
| 5kf1 | COA | Predicted acetyltransferase | / | 0.651 | |
| 3s6f | COA | Uncharacterized protein | / | 0.650 | |
| 4kvm | SER_ALA_SER_GLU_1XE | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.650 |