Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1ozh HE3 Acetolactate synthase, catabolic 2.2.1.6

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1ozh HE3Acetolactate synthase, catabolic 2.2.1.6 1.253
1y9d TPPPyruvate oxidase 1.2.3.3 0.798
1upc TPPN(2)-(2-carboxyethyl)arginine synthase / 0.779
1upa TPPN(2)-(2-carboxyethyl)arginine synthase / 0.762
1upb TPPN(2)-(2-carboxyethyl)arginine synthase / 0.750
2iht TPPN(2)-(2-carboxyethyl)arginine synthase / 0.750
5ahk TPPAcetolactate synthase II, large subunit / 0.741
2ihv TPPN(2)-(2-carboxyethyl)arginine synthase / 0.732
1pox TPPPyruvate oxidase 1.2.3.3 0.723
1pvd TPPPyruvate decarboxylase isozyme 1 / 0.716
2ag1 TPPBenzaldehyde lyase / 0.711
2x7j TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.706
1po7 TZDBenzoylformate decarboxylase 4.1.1.7 0.705
4jd5 TZDBenzoylformate decarboxylase 4.1.1.7 0.703
4juf TPPBenzoylformate decarboxylase 4.1.1.7 0.703
5esd TDP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.703
3ey9 TDPPyruvate dehydrogenase [ubiquinone] 1.2.5.1 0.698
3d7k D7KBenzaldehyde lyase / 0.697
4mzx TZDBenzoylformate decarboxylase 4.1.1.7 0.696
2c3u 2TPPyruvate synthase / 0.695
5exd TPPOxalate oxidoreductase subunit alpha / 0.690
5exd TPPOxalate oxidoreductase subunit beta / 0.690
3fzn D7KBenzoylformate decarboxylase 4.1.1.7 0.689
1bfd TPPBenzoylformate decarboxylase 4.1.1.7 0.688
4ju9 TZDBenzoylformate decarboxylase 4.1.1.7 0.688
5eso TDP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.688
4mpr TPPBenzoylformate decarboxylase 4.1.1.7 0.683
5c4i TPPOxalate oxidoreductase subunit alpha / 0.682
5c4i TPPOxalate oxidoreductase subunit beta / 0.682
5itz GTPTubulin alpha-1B chain / 0.681
5dgt TZDBenzoylformate decarboxylase 4.1.1.7 0.680
3zhv TDWMultifunctional 2-oxoglutarate metabolism enzyme 1.2.4.2 0.678
1jsc TPPAcetolactate synthase catalytic subunit, mitochondrial 2.2.1.6 0.675
1ovm TPPIndole-3-pyruvate decarboxylase 4.1.1.74 0.673
2c3y HTLPyruvate synthase / 0.673
1pow TPPPyruvate oxidase 1.2.3.3 0.671
2ezt TDMPyruvate oxidase 1.2.3.3 0.670
2q5q TPWIndole-3-pyruvate decarboxylase 4.1.1.74 0.669
3fvq ATPFe(3+) ions import ATP-binding protein FbpC / 0.669
4ju8 TZDBenzoylformate decarboxylase 4.1.1.7 0.669
4mq5 TPPBenzoylformate decarboxylase 4.1.1.7 0.669
4qel TZDBenzoylformate decarboxylase 4.1.1.7 0.668
4gm1 TZDBenzoylformate decarboxylase 4.1.1.7 0.667
4zp1 TPPPyruvate decarboxylase 4.1.1.1 0.666
2fwn TDPBenzoylformate decarboxylase 4.1.1.7 0.664
4tuy GTPTubulin alpha-1B chain / 0.664
2vk4 TPPPyruvate decarboxylase 4.1.1.1 0.663
4gm0 TZDBenzoylformate decarboxylase 4.1.1.7 0.662
2ez9 TDKPyruvate oxidase 1.2.3.3 0.660
2ji9 TPWOxalyl-CoA decarboxylase 4.1.1.8 0.659
2q5o TPWIndole-3-pyruvate decarboxylase 4.1.1.74 0.657
2jla TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.654
1kek HTLPyruvate synthase / 0.653
2uz1 TPPBenzaldehyde lyase / 0.653
1nhh ANPDNA mismatch repair protein MutL / 0.652
4mpp TZDBenzoylformate decarboxylase 4.1.1.7 0.652
1aq2 ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.651
2pan TDPGlyoxylate carboligase 4.1.1.47 0.651
3ncq ATPNitrogen regulatory protein P-II (GlnB-2) / 0.651
4db1 ANPMyosin-7 / 0.651