Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1okz UCN 3-phosphoinositide-dependent protein kinase 1 2.7.11.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1okz UCN3-phosphoinositide-dependent protein kinase 1 2.7.11.1 1.210
1oky STU3-phosphoinositide-dependent protein kinase 1 2.7.11.1 1.016
1nvr STUSerine/threonine-protein kinase Chk1 2.7.11.1 0.939
1nvq UCNSerine/threonine-protein kinase Chk1 2.7.11.1 0.894
2clq STUMitogen-activated protein kinase kinase kinase 5 2.7.11.25 0.881
3f69 XDRSerine/threonine-protein kinase PknB 2.7.11.1 0.859
1stc STUcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.851
4c34 STUcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.822
1u59 STUTyrosine-protein kinase ZAP-70 2.7.10.2 0.807
2dq7 STUTyrosine-protein kinase Fyn 2.7.10.2 0.805
2nry STUInterleukin-1 receptor-associated kinase 4 2.7.11.1 0.776
1yhs STUSerine/threonine-protein kinase pim-1 2.7.11.1 0.772
4mvf STUCalcium-dependent protein kinase 2 2.7.11.1 0.772
5e8y STUTGF-beta receptor type-2 2.7.11.30 0.772
1xjd STUProtein kinase C theta type 2.7.11.13 0.765
3cbl STUTyrosine-protein kinase Fes/Fps 2.7.10.2 0.764
1pkd UCNCyclin-dependent kinase 2 2.7.11.22 0.754
4wsq KSAAP2-associated protein kinase 1 2.7.11.1 0.754
5e8w STUTGF-beta receptor type-1 2.7.11.30 0.747
1qpj STUTyrosine-protein kinase Lck 2.7.10.2 0.745
3bkb STUTyrosine-protein kinase Fes/Fps 2.7.10.2 0.742
3zew STUEphrin type-B receptor 4 2.7.10.1 0.733
2j0k 4STFocal adhesion kinase 1 2.7.10.2 0.731
4bf2 STUMitogen-activated protein kinase kinase kinase 5 2.7.11.25 0.722
1byg STUTyrosine-protein kinase CSK / 0.720
1nvs UCMSerine/threonine-protein kinase Chk1 2.7.11.1 0.716
1aq1 STUCyclin-dependent kinase 2 2.7.11.22 0.701
3orz BI43-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.696
2j0j 4STFocal adhesion kinase 1 2.7.10.2 0.687
1yvj 4STTyrosine-protein kinase JAK3 2.7.10.2 0.686
1uu3 LY43-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.684
1x8b 824Wee1-like protein kinase 2.7.10.2 0.682
2erz HFScAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.681
2gcd STUSerine/threonine-protein kinase TAO2 2.7.11.1 0.675
2itq ITQEpidermal growth factor receptor 2.7.10.1 0.669
4c58 824Cyclin-G-associated kinase 2.7.11.1 0.669
2buj STUSerine/threonine-protein kinase 16 / 0.665
3uix Q17Serine/threonine-protein kinase pim-1 2.7.11.1 0.665
3a62 STURibosomal protein S6 kinase beta-1 2.7.11.1 0.664
2yn8 STUEphrin type-B receptor 4 2.7.10.1 0.663
1uu9 BI33-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.661
3a60 STURibosomal protein S6 kinase beta-1 2.7.11.1 0.659
3ckx STUSerine/threonine-protein kinase 24 2.7.11.1 0.659
4bib IEOMitogen-activated protein kinase kinase kinase 5 2.7.11.25 0.659
2hy8 1STSerine/threonine-protein kinase PAK 1 2.7.11.1 0.653