sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1ogj | FAD | Ferredoxin--NADP reductase | 1.18.1.2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 1ogj | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.384 | |
| 1ogi | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.362 | |
| 1h42 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.306 | |
| 1bjk | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.305 | |
| 1e63 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.292 | |
| 1go2 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.279 | |
| 1e64 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.262 | |
| 1gr1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.261 | |
| 1qgy | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.254 | |
| 3zbt | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.254 | |
| 4c43 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.248 | |
| 1e62 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.247 | |
| 1gjr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.242 | |
| 1h85 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.240 | |
| 1que | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.235 | |
| 1qh0 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.234 | |
| 1w35 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.218 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.218 | |
| 1b2r | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.217 | |
| 3mhp | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 1.215 | |
| 1qg0 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 1.203 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.201 | |
| 1gaw | FAD | Ferredoxin | / | 1.194 | |
| 1fnc | FDA | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 1.188 | |
| 3vo2 | FAD | Ferredoxin--NADP reductase | / | 1.183 | |
| 1bx1 | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 1.179 | |
| 1fnd | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 1.177 | |
| 1fnb | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 1.176 | |
| 1bx0 | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 1.172 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.169 | |
| 2b5o | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.160 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 1.155 | |
| 4bpr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.151 | |
| 3w5u | FAD | Ferredoxin | / | 1.145 | |
| 1qgz | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.120 | |
| 2rc5 | FAD | Ferredoxin--NADP reductase | / | 1.084 | |
| 1sm4 | FAD | Ferredoxin--NADP reductase | / | 1.079 | |
| 1gaq | FAD | Ferredoxin | / | 1.073 | |
| 2rc6 | FAD | Ferredoxin--NADP reductase | / | 1.072 | |
| 1ewy | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.024 | |
| 1w87 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 1.009 | |
| 4af6 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 1.007 | |
| 4yaf | FAD | NADPH--cytochrome P450 reductase | / | 1.006 | |
| 3qfc | FAD | NADPH--cytochrome P450 reductase | / | 0.967 | |
| 3qft | FAD | NADPH--cytochrome P450 reductase | / | 0.958 | |
| 3qfs | FAD | NADPH--cytochrome P450 reductase | / | 0.956 | |
| 2xnc | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.951 | |
| 3ojw | FAD | NADPH--cytochrome P450 reductase | / | 0.947 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.945 | |
| 3jqr | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.940 | |
| 4yau | FAD | NADPH--cytochrome P450 reductase | / | 0.933 | |
| 1ja1 | FAD | NADPH--cytochrome P450 reductase | / | 0.926 | |
| 1tll | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.924 | |
| 4y7c | FAD | NADPH--cytochrome P450 reductase | / | 0.924 | |
| 2bf4 | FAD | NADPH--cytochrome P450 reductase | / | 0.913 | |
| 4uaj | FAD | Na(+)-translocating NADH-quinone reductase subunit F | / | 0.911 | |
| 4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.902 | |
| 4y9u | FAD | NADPH--cytochrome P450 reductase | / | 0.901 | |
| 3w5h | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.887 | |
| 2ok8 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.883 | |
| 3ojx | FAD | NADPH--cytochrome P450 reductase | / | 0.872 | |
| 3qfr | FAD | NADPH--cytochrome P450 reductase | / | 0.871 | |
| 1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.870 | |
| 3qe2 | FAD | NADPH--cytochrome P450 reductase | / | 0.858 | |
| 2ok7 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.857 | |
| 4yao | FAD | NADPH--cytochrome P450 reductase | / | 0.855 | |
| 4y9r | FAD | NADPH--cytochrome P450 reductase | / | 0.840 | |
| 1umk | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.835 | |
| 1cqx | FAD | Flavohemoprotein | / | 0.827 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.810 | |
| 2eix | FAD | NADH-cytochrome b5 reductase | / | 0.807 | |
| 2bn4 | FAD | NADPH--cytochrome P450 reductase | / | 0.806 | |
| 1amo | FAD | NADPH--cytochrome P450 reductase | / | 0.795 | |
| 2r6h | FAD | Na(+)-translocating NADH-quinone reductase subunit F | / | 0.794 | |
| 3w2f | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.772 | |
| 1krh | FAD | Benzoate 1,2-dioxygenase electron transfer component | 1.18.1.3 | 0.754 | |
| 2gpj | FAD | Siderophore-interacting protein | / | 0.751 | |
| 3w2e | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.732 | |
| 1gvh | FAD | Flavohemoprotein | / | 0.726 | |
| 2cnd | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.724 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.710 | |
| 3crz | FAD | Ferredoxin--NADP+ reductase | / | 0.708 | |
| 4ybn | FAD | Flavin-nucleotide-binding protein | / | 0.700 | |
| 2bpo | FAD | NADPH--cytochrome P450 reductase | / | 0.699 | |
| 2vnh | FAD | NADPH:ferredoxin reductase | / | 0.698 | |
| 2y48 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.698 | |
| 2dji | FAD | Pyruvate oxidase | / | 0.692 | |
| 1ep3 | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit | / | 0.691 | |
| 4iv6 | FDA | Isovaleryl-CoA dehydrogenase | / | 0.690 | |
| 1rz1 | FAD | Phenol 2-hydroxylase component B | / | 0.689 | |
| 1h83 | FAD | Polyamine oxidase | 1.5.3.14 | 0.688 | |
| 3fpk | FAD | Ferredoxin-NADP reductase | / | 0.687 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.687 | |
| 2ptf | FMN | Uncharacterized protein MTH_863 | / | 0.685 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.685 | |
| 3a6q | FMN | FMN-binding protein | / | 0.684 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.684 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.683 | |
| 2iml | FMN | Uncharacterized protein | / | 0.680 | |
| 1fdr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.679 | |
| 4mo2 | FAD | UDP-galactopyranose mutase | / | 0.679 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.678 | |
| 2pia | FMN | Phthalate dioxygenase reductase | / | 0.678 | |
| 4iil | RBF | Membrane lipoprotein TpN38(b) | / | 0.678 | |
| 3q9t | FAY | Uncharacterized protein | / | 0.676 | |
| 3a20 | FMN | FMN-binding protein | / | 0.675 | |
| 5j60 | FAD | Thioredoxin reductase | / | 0.675 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.673 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.671 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.671 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.671 | |
| 3a6r | FMN | FMN-binding protein | / | 0.667 | |
| 3vy2 | FMN | FMN-binding protein | / | 0.667 | |
| 3a3b | RBF | Lumazine protein | / | 0.665 | |
| 3if9 | FAD | Glycine oxidase | 1.4.3.19 | 0.665 | |
| 4a30 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.665 | |
| 5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.665 | |
| 2bab | FAD | Putative aminooxidase | / | 0.664 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.664 | |
| 1v5e | FAD | Pyruvate oxidase | / | 0.663 | |
| 3lov | FAD | Protoporphyrinogen oxidase | / | 0.663 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.662 | |
| 2bi8 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.662 | |
| 2c3d | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.662 | |
| 2e83 | FMN | FMN-binding protein | / | 0.658 | |
| 1tj2 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.656 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.656 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.655 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.653 | |
| 2ard | FDA | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.653 | |
| 2z6c | FMN | Phototropin-1 | 2.7.11.1 | 0.652 | |
| 2gj3 | FAD | Nitrogen fixation regulatory protein | 2.7.13.3 | 0.651 | |
| 3awh | FMN | FMN-binding protein | / | 0.651 | |
| 3e4v | FMN | Uncharacterized protein | / | 0.651 | |
| 4fdn | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.651 | |
| 4k1x | FAD | NADPH:ferredoxin reductase | / | 0.651 | |
| 4rhe | FMN | Flavin prenyltransferase UbiX | / | 0.651 |