Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1o29 FAD Flavin-dependent thymidylate synthase 2.1.1.148

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1o29 FADFlavin-dependent thymidylate synthase 2.1.1.148 1.372
5ios FADFlavin-dependent thymidylate synthase 2.1.1.148 1.201
3n0c FADFlavin-dependent thymidylate synthase 2.1.1.148 1.140
3g4a FADFlavin-dependent thymidylate synthase 2.1.1.148 1.111
3n0b FADFlavin-dependent thymidylate synthase 2.1.1.148 1.093
1kq4 FADFlavin-dependent thymidylate synthase 2.1.1.148 0.977
4p5a FADFlavin-dependent thymidylate synthase / 0.965
4gte FADFlavin-dependent thymidylate synthase 2.1.1.148 0.947
4gtl FADFlavin-dependent thymidylate synthase 2.1.1.148 0.918
2af6 FADFlavin-dependent thymidylate synthase 2.1.1.148 0.850
3gwc FADFlavin-dependent thymidylate synthase 2.1.1.148 0.848
3ah5 FADFlavin-dependent thymidylate synthase 2.1.1.148 0.825
4p5b FADFlavin-dependent thymidylate synthase / 0.780
4kar FADFlavin-dependent thymidylate synthase 2.1.1.148 0.692
3enk UPGUDP-glucose 4-epimerase / 0.675
1a9z UPGUDP-glucose 4-epimerase 5.1.3.2 0.673
1udb UFGUDP-glucose 4-epimerase 5.1.3.2 0.665
1rp7 TZDPyruvate dehydrogenase E1 component 1.2.4.1 0.661
3sl2 ATPSensor histidine kinase WalK / 0.656
1xel UPGUDP-glucose 4-epimerase 5.1.3.2 0.653
2vp4 DCPDeoxynucleoside kinase / 0.653
1ytm ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.651
3hzg FADFlavin-dependent thymidylate synthase 2.1.1.148 0.651
4a3u FMNNADH:flavin oxidoreductase/NADH oxidase / 0.650