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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1o1s 1NH Protein farnesyltransferase subunit beta 2.5.1.58

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1o1s 1NHProtein farnesyltransferase subunit beta 2.5.1.58 1.311
3eu5 GBOProtein farnesyltransferase subunit beta 2.5.1.58 0.882
3ksl SZHProtein farnesyltransferase subunit beta 2.5.1.58 0.790
1n95 HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha / 0.668
1n95 HFPProtein farnesyltransferase subunit beta 2.5.1.58 0.668
4gte FADFlavin-dependent thymidylate synthase 2.1.1.148 0.665
4mkg AP5Adenylate kinase / 0.656
3ez3 IPEFarnesyl pyrophosphate synthase, putative / 0.654
2wog ZZDKinesin-like protein KIF11 / 0.652