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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1nv9 SAH Release factor glutamine methyltransferase 2.1.1.297

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1nv9 SAHRelease factor glutamine methyltransferase 2.1.1.297 0.862
1sg9 SAMRelease factor glutamine methyltransferase 2.1.1.297 0.762
3cjt SAHRibosomal protein L11 methyltransferase 2.1.1 0.734
3cjq SAHRibosomal protein L11 methyltransferase 2.1.1 0.730
1nv8 SAMRelease factor glutamine methyltransferase 2.1.1.297 0.727
1vq1 SAMRelease factor glutamine methyltransferase 2.1.1.297 0.710
3egv SAHRibosomal protein L11 methyltransferase 2.1.1 0.703
2h00 SAHU6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase / 0.695
3b3f SAHHistone-arginine methyltransferase CARM1 / 0.690
2gs9 SAHUncharacterized protein / 0.687
2vdv SAMtRNA (guanine-N(7)-)-methyltransferase / 0.685
2bzg SAHThiopurine S-methyltransferase 2.1.1.67 0.683
2y1x SAHHistone-arginine methyltransferase CARM1 / 0.682
3iei SAHLeucine carboxyl methyltransferase 1 2.1.1.233 0.681
2v74 SAHHistone-arginine methyltransferase CARM1 / 0.679
2nxe SAMRibosomal protein L11 methyltransferase 2.1.1 0.675
1f3l SAHProtein arginine N-methyltransferase 3 / 0.674
3dmg SAHProbable ribosomal RNA small subunit methyltransferase / 0.674
5dxj SFGHistone-arginine methyltransferase CARM1 / 0.673
3lcc SAHThiocyanate methyltransferase 1 / 0.672
4dcm SAMRibosomal RNA large subunit methyltransferase G 2.1.1.174 0.672
1rjd SAMLeucine carboxyl methyltransferase 1 2.1.1.233 0.669
3lcu SAH16S rRNA (guanine(1405)-N(7))-methyltransferase 2.1.1.179 0.669
5dxa SFGHistone-arginine methyltransferase CARM1 / 0.669
3fri SAH16S rRNA methylase / 0.666
3lcv SAM16S rRNA (guanine(1405)-N(7))-methyltransferase 2.1.1.179 0.666
4qdk SAHMagnesium-protoporphyrin O-methyltransferase 2.1.1.11 0.666
5epe SAHUncharacterized protein / 0.666
1rje SAHLeucine carboxyl methyltransferase 1 2.1.1.233 0.665
4azw SAMO-antigen chain terminator bifunctional methyltransferase/kinase WbdD / 0.665
5je2 SAHMethyl transferase / 0.664
4c03 SFGProtein arginine N-methyltransferase 6 / 0.662
5icf SAH(S)-norcoclaurine 6-O-methyltransferase / 0.662
2yqz SAMUncharacterized protein / 0.661
3gwz SAHMitomycin biosynthesis 6-O-methyltransferase / 0.658
2bh2 SAH23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD / 0.657
3e23 SAMUncharacterized protein / 0.657
4lwp SAHArginine N-methyltransferase, putative / 0.656
4rvd SAMD-mycarose 3-C-methyltransferase / 0.656
4ax8 SAMO-antigen chain terminator bifunctional methyltransferase/kinase WbdD / 0.654
5jr3 SAHCarminomycin 4-O-methyltransferase DnrK 2.1.1.292 0.654
4iv0 SAMPhosphoethanolamine N-methyltransferase, putative / 0.652
4uy6 SAHHistidine N-alpha-methyltransferase / 0.651
3dmh SAMProbable ribosomal RNA small subunit methyltransferase / 0.650