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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1nce CB3 Thymidylate synthase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1nce CB3Thymidylate synthase / 0.940
1bq1 CB3Thymidylate synthase / 0.777
2fto CB3Thymidylate synthase / 0.751
1tdu CB3Thymidylate synthase / 0.731
1aiq CB3Thymidylate synthase / 0.725
1trg CB3Thymidylate synthase / 0.724
1kce CB3Thymidylate synthase / 0.710
4gev CB3Thymidylate synthase / 0.704
1dna CB3Thymidylate synthase / 0.695
2bbq PFGThymidylate synthase / 0.691
1zpr CB3Thymidylate synthase / 0.686
2tsc CB3Thymidylate synthase / 0.682
4knz CB3Thymidylate synthase / 0.682
1an5 CB3Thymidylate synthase / 0.679
1ddu CB3Thymidylate synthase / 0.674
2aaz CB3Thymidylate synthase 2.1.1.45 0.674
1tys DHFThymidylate synthase / 0.668