Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1me6 IVS Plasmepsin-2 3.4.23.39

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1me6 IVSPlasmepsin-2 3.4.23.39 1.261
1xe6 5FPPlasmepsin-2 3.4.23.39 0.889
1w6h TITPlasmepsin-2 3.4.23.39 0.682
1xe5 5FEPlasmepsin-2 3.4.23.39 0.681
1psa 0ZLPepsin A 3.4.23.1 0.676
1b11 3TLPol polyprotein / 0.661
1qrp HH0Pepsin A-4 3.4.23.1 0.654
1rne C60Renin 3.4.23.15 0.654