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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1mdr APG Mandelate racemase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1mdr APGMandelate racemase / 0.983
1mdl SMNMandelate racemase / 0.841
4hnc 0UTMandelate racemase / 0.836
1dtn APGMandelate racemase / 0.792
1mra APGMandelate racemase / 0.756
3w2w ATPCRISPR system Cmr subunit Cmr2 / 0.673
3ahi HTLProbable phosphoketolase / 0.662
1rp7 TZDPyruvate dehydrogenase E1 component 1.2.4.1 0.661
2g28 TDKPyruvate dehydrogenase E1 component 1.2.4.1 0.660
2hru ADPPhosphoribosylformylglycinamidine synthase subunit PurL / 0.658
5fhq DNCCatechol O-methyltransferase 2.1.1.6 0.658
1r6w 164o-succinylbenzoate synthase / 0.655
3qj5 022Alcohol dehydrogenase class-3 1.1.1.1 0.653
3zhr TPPMultifunctional 2-oxoglutarate metabolism enzyme 1.2.4.2 0.653
3zhq TPPMultifunctional 2-oxoglutarate metabolism enzyme 1.2.4.2 0.652
3zhs TD6Multifunctional 2-oxoglutarate metabolism enzyme 1.2.4.2 0.650