sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1lot | ATP | Actin, alpha skeletal muscle |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 1lot | ATP | Actin, alpha skeletal muscle | / | 1.143 | |
| 1eqy | ATP | Actin, alpha skeletal muscle | / | 0.944 | |
| 3mn9 | ATP | Actin-5C | / | 0.928 | |
| 3a5o | ATP | Major actin | / | 0.925 | |
| 1qz5 | ATP | Actin, alpha skeletal muscle | / | 0.921 | |
| 1mdu | ATP | Actin, alpha skeletal muscle | / | 0.915 | |
| 3m1f | ATP | Actin, alpha skeletal muscle | / | 0.911 | |
| 4pki | ATP | Actin, alpha skeletal muscle | / | 0.910 | |
| 1kxp | ATP | Actin, alpha skeletal muscle | / | 0.909 | |
| 2q36 | ATP | Actin, alpha skeletal muscle | / | 0.909 | |
| 1t44 | ATP | Actin, alpha skeletal muscle | / | 0.905 | |
| 4k41 | ATP | Actin, alpha skeletal muscle | / | 0.905 | |
| 1s22 | ATP | Actin, alpha skeletal muscle | / | 0.904 | |
| 3ffk | ATP | Actin, alpha skeletal muscle | / | 0.900 | |
| 4b1v | ATP | Actin, alpha skeletal muscle | / | 0.891 | |
| 1wua | ATP | Actin, alpha skeletal muscle | / | 0.890 | |
| 1dej | ATP | Major actin | / | 0.875 | |
| 3eks | ATP | Actin-5C | / | 0.874 | |
| 4cbx | ATP | Actin-2 | / | 0.873 | |
| 2q97 | ATP | Actin, alpha skeletal muscle | / | 0.871 | |
| 2oan | ATP | Actin, cytoplasmic 1 | / | 0.870 | |
| 4pkg | ATP | Actin, alpha skeletal muscle | / | 0.869 | |
| 3w3d | ATP | Actin, gamma-enteric smooth muscle | / | 0.867 | |
| 4pl8 | ATP | Actin, alpha skeletal muscle | / | 0.863 | |
| 3mn6 | ATP | Actin-5C | / | 0.862 | |
| 3mn7 | ATP | Actin-5C | / | 0.860 | |
| 1c0f | ATP | Major actin | / | 0.854 | |
| 3tu5 | ATP | Actin, alpha skeletal muscle | / | 0.854 | |
| 3daw | ATP | Actin, alpha skeletal muscle | / | 0.846 | |
| 2a41 | ATP | Actin, alpha skeletal muscle | / | 0.843 | |
| 3eku | ATP | Actin-5C | / | 0.837 | |
| 3el2 | ATP | Actin-5C | / | 0.827 | |
| 1rfq | ATP | Actin, alpha skeletal muscle | / | 0.825 | |
| 3chw | ATP | Major actin | / | 0.821 | |
| 1nlv | ATP | Major actin | / | 0.813 | |
| 2p9k | ATP | Actin-related protein 2 | / | 0.809 | |
| 4m63 | ATP | Actin-5C | / | 0.807 | |
| 5ce3 | ATP | Actin | / | 0.807 | |
| 3wt0 | ATP | Cell division protein FtsA | / | 0.803 | |
| 4ci6 | ATP | Actin | / | 0.794 | |
| 4pkh | ADP | Actin, alpha skeletal muscle | / | 0.791 | |
| 3a5m | ATP | Major actin | / | 0.788 | |
| 3m6g | ATP | Actin, alpha skeletal muscle | / | 0.788 | |
| 1ijj | ATP | Actin, alpha skeletal muscle | / | 0.782 | |
| 1rgi | ATP | Actin, alpha skeletal muscle | / | 0.777 | |
| 1atn | ATP | Actin, alpha skeletal muscle | / | 0.768 | |
| 2v51 | ATP | Actin, alpha skeletal muscle | / | 0.749 | |
| 4a62 | ANP | Plasmid segregation protein ParM | / | 0.749 | |
| 4ehu | ANP | 2-hydroxyisocaproyl-CoA dehydratase activator | / | 0.748 | |
| 1nmd | ATP | Major actin | / | 0.735 | |
| 2zgy | GDP | Plasmid segregation protein ParM | / | 0.724 | |
| 1yxq | ATP | Actin, alpha skeletal muscle | / | 0.722 | |
| 2zgz | GNP | Plasmid segregation protein ParM | / | 0.704 | |
| 4eht | ADP | 2-hydroxyisocaproyl-CoA dehydratase activator | / | 0.698 | |
| 4brg | GNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.697 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.696 | |
| 4k42 | ADP | Actin, alpha skeletal muscle | / | 0.696 | |
| 4a61 | ANP | Plasmid segregation protein ParM | / | 0.693 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.691 | |
| 3ule | ATP | Actin-related protein 2 | / | 0.686 | |
| 3wqt | ANP | Cell division protein FtsA | / | 0.685 | |
| 3d2e | ATP | Heat shock protein homolog SSE1 | / | 0.684 | |
| 1h1v | ATP | Actin, alpha skeletal muscle | / | 0.683 | |
| 5itz | GTP | Tubulin alpha-1B chain | / | 0.682 | |
| 3ldl | ATP | 78 kDa glucose-regulated protein | / | 0.677 | |
| 3orl | AGS | Serine/threonine protein kinase | / | 0.677 | |
| 5eoy | ADP | Type 4 fimbrial biogenesis protein PilM | / | 0.677 | |
| 4k43 | ADP | Actin, alpha skeletal muscle | / | 0.674 | |
| 4to4 | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.673 | |
| 4h5d | YS4 | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.669 | |
| 4h5c | YS4 | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.666 | |
| 2fsn | ADP | Archaeal actin homolog | / | 0.663 | |
| 4dem | YS4 | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.662 | |
| 2e2q | ADP | ATP-dependent hexokinase | / | 0.660 | |
| 2x60 | GTP | Mannose-1-phosphate guanylyltransferase | / | 0.660 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.657 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.657 | |
| 4nke | RIS | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.657 | |
| 2cea | ADP | ATP-dependent zinc metalloprotease FtsH | / | 0.655 | |
| 3k8t | DGT | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.653 | |
| 4jlo | ADP | Adenylate kinase | / | 0.652 | |
| 4lfv | YS4 | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.652 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.651 | |
| 2olq | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.650 | |
| 4kqs | RIS | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.650 |