Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1lj8 NAD Mannitol dehydrogenase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1lj8 NADMannitol dehydrogenase / 1.124
5a02 NAPGlucose-fructose oxidoreductase / 0.667
1yjq NAP2-dehydropantoate 2-reductase 1.1.1.169 0.665
2rcy NAPPyrroline-5-carboxylate reductase / 0.661
1h6a NDPGlucose--fructose oxidoreductase 1.1.99.28 0.658
2g5c NADPrephenate dehydrogenase / 0.656
4dpl NAPMalonyl-CoA reductase 1.2.1.75 0.654
5a06 NDPGlucose-fructose oxidoreductase / 0.654
5bsf NADPyrroline-5-carboxylate reductase / 0.650