Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1jue FMN Dihydroorotate dehydrogenase A (fumarate) 1.3.98.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1jue FMNDihydroorotate dehydrogenase A (fumarate) 1.3.98.1 1.165
1jub FMNDihydroorotate dehydrogenase A (fumarate) 1.3.98.1 1.161
2bsl FMNDihydroorotate dehydrogenase A (fumarate) 1.3.98.1 1.118
2djl FMNDihydroorotate dehydrogenase (fumarate) 1.3.98.1 1.108
2djx FMNDihydroorotate dehydrogenase (fumarate) 1.3.98.1 1.101
4ef9 FMNDihydroorotate dehydrogenase (fumarate) / 1.096
4ef8 FMNDihydroorotate dehydrogenase (fumarate) / 1.095
1dor FMNDihydroorotate dehydrogenase A (fumarate) 1.3.98.1 1.091
4wzh FMNDihydroorotate dehydrogenase (fumarate) / 1.065
3gye FMNDihydroorotate dehydrogenase (fumarate) / 1.052
3c3n FMNDihydroorotate dehydrogenase (fumarate) 1.3.98.1 1.003
3oix FMNDihydroorotate dehydrogenase / 0.981
4uth FMNXenobiotic reductase / 0.851
4utl FNRXenobiotic reductase / 0.851
1ep3 FMNDihydroorotate dehydrogenase B (NAD(+)), catalytic subunit 1.3.1.14 0.849
4aws FMNNADH:flavin oxidoreductase Sye1 / 0.847
1ics FMN12-oxophytodienoate reductase 1 1.3.1.42 0.836
1z48 FMNNADPH dehydrogenase / 0.836
3hf3 FMNChromate reductase / 0.836
3l5l FMNXenobiotic reductase / 0.836
4awt FMNNADH:flavin oxidoreductase Sye1 / 0.830
4tmc FMNOld yellow enzyme / 0.828
4df2 FMNNADPH dehydrogenase / 0.827
3l67 FMNXenobiotic reductase / 0.824
4utm FNRXenobiotic reductase / 0.824
1h7w FMNDihydropyrimidine dehydrogenase [NADP(+)] 1.3.1.2 0.820
2hsa FMN12-oxophytodienoate reductase 3 1.3.1.42 0.819
3kru FMNNADH:flavin oxidoreductase/NADH oxidase / 0.817
1ep1 FMNDihydroorotate dehydrogenase B (NAD(+)), catalytic subunit 1.3.1.14 0.815
3n19 FNRXenobiotic reductase / 0.814
2gqa FMNNADH:flavin oxidoreductase Sye1 / 0.813
3hgr FMN12-oxophytodienoate reductase 1 1.3.1.42 0.812
4h6k FMNNADPH dehydrogenase 1 1.6.99.1 0.812
3n14 FMNXenobiotic reductase / 0.808
4tmb FMNOld yellow enzyme / 0.807
1oya FMNNADPH dehydrogenase 1 1.6.99.1 0.804
4xq6 FMNDihydroorotate dehydrogenase (quinone) / 0.804
1gwj FMNMorphinone reductase / 0.802
4utk FNRXenobiotic reductase / 0.801
2zru FMNIsopentenyl-diphosphate delta-isomerase / 0.788
2hs8 FMN12-oxophytodienoate reductase 3 1.3.1.42 0.787
1h63 FMNPentaerythritol tetranitrate reductase / 0.784
3gr8 FMNNADPH dehydrogenase / 0.784
3hgs FMN12-oxophytodienoate reductase 3 1.3.1.42 0.774
1z41 FMNNADPH dehydrogenase / 0.772
2hs6 FMN12-oxophytodienoate reductase 3 1.3.1.42 0.772
1vji FMN12-oxophytodienoate reductase 1 1.3.1.42 0.771
4qnw FMNChanoclavine-I aldehyde reductase easA / 0.767
1oyc FMNNADPH dehydrogenase 1 1.6.99.1 0.766
3p74 FMNPentaerythritol tetranitrate reductase / 0.764
3p62 FMNPentaerythritol tetranitrate reductase / 0.762
1q45 FMN12-oxophytodienoate reductase 3 1.3.1.42 0.760
2abb FMNPentaerythritol tetranitrate reductase / 0.760
1z44 FMNNADPH dehydrogenase / 0.757
1llw FMNFerredoxin-dependent glutamate synthase 2 1.4.7.1 0.751
1ofd FMNFerredoxin-dependent glutamate synthase 2 1.4.7.1 0.751
3p82 FMNPentaerythritol tetranitrate reductase / 0.751
1h50 FMNPentaerythritol tetranitrate reductase / 0.747
1vhn FMNtRNA-dihydrouridine synthase / 0.747
3p8j FMNPentaerythritol tetranitrate reductase / 0.746
2z6i FMN2-nitropropane dioxygenase / 0.745
1bwl FMNNADPH dehydrogenase 1 1.6.99.1 0.739
2gjl FMNNitronate monooxygenase 1.13.12.16 0.735
3p8i FMNPentaerythritol tetranitrate reductase / 0.732
1vyr FMNPentaerythritol tetranitrate reductase / 0.731
3p84 FMNPentaerythritol tetranitrate reductase / 0.731
3f03 FMNPentaerythritol tetranitrate reductase / 0.730
1lm1 FMNFerredoxin-dependent glutamate synthase 2 1.4.7.1 0.728
1ofe FMNFerredoxin-dependent glutamate synthase 2 1.4.7.1 0.728
3tjl FMNNADPH dehydrogenase / 0.727
4rnw FMNNADPH dehydrogenase 1 1.6.99.1 0.726
1uum FMNDihydroorotate dehydrogenase (quinone), mitochondrial 1.3.5.2 0.723
2j6x FMNLactate oxidase / 0.722
4m5p FMNNADPH dehydrogenase / 0.719
1h51 FMNPentaerythritol tetranitrate reductase / 0.718
2du2 FMNLactate oxidase / 0.717
5ebu FMNLactate oxidase / 0.709
2nli FMNLactate oxidase / 0.707
4rje FNRLactate oxidase / 0.707
3gka FMNN-ethylmaleimide reductase / 0.706
4cw5 FMNDfnA / 0.704
1gox FMNPeroxisomal (S)-2-hydroxy-acid oxidase 1.1.3.15 0.702
4iql FMNEnoyl-(Acyl-carrier-protein) reductase II / 0.702
4bf9 FMNtRNA-dihydrouridine(16) synthase / 0.701
4qai FMNNADPH dehydrogenase / 0.698
4jic FMNGTN Reductase / 0.695
4ycp FMNtRNA-dihydrouridine(16) synthase / 0.693
1bwk FMNNADPH dehydrogenase 1 1.6.99.1 0.682
4k7y FMNNADPH dehydrogenase 1 1.6.99.1 0.679
4hia FMNLOV protein / 0.677
4rnv FMNNADPH dehydrogenase 1 1.6.99.1 0.676
4e2d FMNDehydrogenase / 0.675
2gou FMNNADH:flavin oxidoreductase Sye1 / 0.673
2h8x FMNXenA / 0.672
2e77 FMNLactate oxidase / 0.671
4ttc FMNIodotyrosine deiodinase 1 / 0.671
3bw3 FMNPutative 2-nitropropane dioxygenase / 0.669
2zry FNRIsopentenyl-diphosphate delta-isomerase / 0.668
1vcf FMNIsopentenyl-diphosphate delta-isomerase / 0.667
4e2b FMNDehydrogenase / 0.666
2ohj FMNType A flavoprotein FprA 1 0.664
3qe2 FMNNADPH--cytochrome P450 reductase / 0.662
1r2j FADFkbI / 0.661
3w77 FMNFMN-dependent NADH-azoreductase / 0.660
4n65 FMNFMN-dependent NADH-azoreductase 1 / 0.659
5af7 FADAcyl-CoA dehydrogenase / 0.659
1k02 FMNNADPH dehydrogenase 1 1.6.99.1 0.658
1szg FNSCytochrome b2, mitochondrial 1.1.2.3 0.657
2rhg IGPTryptophan synthase alpha chain / 0.657
1qx4 FADNADH-cytochrome b5 reductase 3 1.6.2.2 0.656
3aty FMNProstaglandin F2a synthase / 0.656
4yl2 FMNLactate oxidase / 0.656
4b5n FMNNAD(P)H:flavin oxidoreductase Sye4 / 0.653
4yco FMNtRNA-dihydrouridine(16) synthase / 0.653
4z9r FMNOmega-3 polyunsaturated fatty acid synthase subunit PfaD / 0.653
2bf4 FMNNADPH--cytochrome P450 reductase / 0.650
3hgo FMN12-oxophytodienoate reductase 3 1.3.1.42 0.650
4zvn FADRibosyldihydronicotinamide dehydrogenase [quinone] / 0.650