Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1iep STI Tyrosine-protein kinase ABL1 2.7.10.2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1iep STITyrosine-protein kinase ABL1 2.7.10.2 1.214
2e2b 406Tyrosine-protein kinase ABL1 2.7.10.2 1.115
2hyy STITyrosine-protein kinase ABL1 2.7.10.2 1.100
3gvu STIAbelson tyrosine-protein kinase 2 2.7.10.2 1.058
3oez STIProto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.979
2oiq STIProto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.950
3cs9 NILTyrosine-protein kinase ABL1 2.7.10.2 0.901
4r7i STIMacrophage colony-stimulating factor 1 receptor 2.7.10.1 0.882
4bkj STIEpithelial discoidin domain-containing receptor 1 2.7.10.1 0.878
2pl0 STITyrosine-protein kinase Lck 2.7.10.2 0.861
2hiw 7MPTyrosine-protein kinase ABL1 2.7.10.2 0.847
4equ G6ISerine/threonine-protein kinase 10 2.7.11.1 0.787
4ckr DI1Epithelial discoidin domain-containing receptor 1 2.7.10.1 0.780
3bv3 P39Mitogen-activated protein kinase 14 / 0.757
3kq7 KQ7Mitogen-activated protein kinase 14 / 0.757
4i5h G17Mitogen-activated protein kinase 1 2.7.11.24 0.746
3bv2 P38Mitogen-activated protein kinase 14 / 0.740
2osc MUHAngiopoietin-1 receptor 2.7.10.1 0.706
3b2w 9NHTyrosine-protein kinase Lck 2.7.10.2 0.699
3mvm 39PMitogen-activated protein kinase 14 / 0.697
3bx5 304Mitogen-activated protein kinase 14 / 0.695
3d83 GK6Mitogen-activated protein kinase 14 / 0.694
4kip 1R9Mitogen-activated protein kinase 14 / 0.691
2ofv 242Tyrosine-protein kinase Lck 2.7.10.2 0.675
4tyj 0LIFibroblast growth factor receptor 4 2.7.10.1 0.674
3be2 RAJVascular endothelial growth factor receptor 2 2.7.10.1 0.672
3vnt 0JAVascular endothelial growth factor receptor 2 2.7.10.1 0.667
2y6o 1N1Ephrin type-A receptor 4 2.7.10.1 0.664
4v01 0LIFibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b / 0.664
3ocg OCGMitogen-activated protein kinase 14 / 0.663
2og8 1N8Tyrosine-protein kinase Lck 2.7.10.2 0.652