sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 1.542 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.786 | |
| 2yja | EST | Estrogen receptor | / | 0.746 | |
| 1gwr | EST | Estrogen receptor | / | 0.744 | |
| 5hyr | EST | Estrogen receptor | / | 0.732 | |
| 4oed | DHT | Androgen receptor | / | 0.730 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.729 | |
| 2ocf | EST | Estrogen receptor | / | 0.728 | |
| 3uud | EST | Estrogen receptor | / | 0.725 | |
| 1t5z | DHT | Androgen receptor | / | 0.721 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.719 | |
| 5dxg | EST | Estrogen receptor | / | 0.718 | |
| 4pxm | EST | Estrogen receptor | / | 0.713 | |
| 1t7t | DHT | Androgen receptor | / | 0.707 | |
| 1t7r | DHT | Androgen receptor | / | 0.704 | |
| 2qgt | EED | Estrogen receptor | / | 0.694 | |
| 1zhy | CLR | Oxysterol-binding protein homolog 4 | / | 0.692 | |
| 1lhu | EST | Sex hormone-binding globulin | / | 0.685 | |
| 3vhu | SNL | Mineralocorticoid receptor | / | 0.682 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.680 | |
| 2ylp | TES | Androgen receptor | / | 0.676 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.674 | |
| 2pix | DHT | Androgen receptor | / | 0.673 | |
| 3fzw | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.670 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.669 | |
| 1sqn | NDR | Progesterone receptor | / | 0.668 | |
| 2w8y | NDR | Progesterone receptor | / | 0.667 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.663 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.660 | |
| 1qyx | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.660 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.657 | |
| 4ofr | DHT | Androgen receptor | / | 0.656 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.655 | |
| 2aa7 | 1CA | Mineralocorticoid receptor | / | 0.654 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.653 | |
| 3lnv | 1ZZ | Saframycin Mx1 synthetase B | / | 0.651 | |
| 4c2x | NHW | Glycylpeptide N-tetradecanoyltransferase 2 | / | 0.651 | |
| 2b1z | 17M | Estrogen receptor | / | 0.650 | |
| 2mm3 | CHO | Gastrotropin | / | 0.650 |