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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1h72 ANP Homoserine kinase 2.7.1.39

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
1h72 ANPHomoserine kinase 2.7.1.39 1.008
1h74 AGSHomoserine kinase 2.7.1.39 0.713
1h74 ADPHomoserine kinase 2.7.1.39 0.683
1h73 ANPHomoserine kinase 2.7.1.39 0.679