sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1h50 | FMN | Pentaerythritol tetranitrate reductase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 1.286 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 1.278 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 1.274 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 1.238 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 1.230 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 1.222 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 1.220 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 1.184 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 1.167 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 1.122 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 1.118 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 1.116 | |
| 4b5n | FMN | NAD(P)H:flavin oxidoreductase Sye4 | / | 1.106 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 1.101 | |
| 4rnx | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 1.097 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 1.085 | |
| 4aws | FMN | NADH:flavin oxidoreductase Sye1 | / | 1.071 | |
| 1oya | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 1.065 | |
| 4h6k | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 1.063 | |
| 4k7y | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 1.063 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 1.057 | |
| 4tmc | FMN | Old yellow enzyme | / | 1.053 | |
| 4a3u | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 1.047 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 1.045 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 1.031 | |
| 1bwk | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 1.014 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 1.014 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 1.001 | |
| 3tjl | FMN | NADPH dehydrogenase | / | 0.992 | |
| 4e2d | FMN | Dehydrogenase | / | 0.982 | |
| 1oyc | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.967 | |
| 4tmb | FMN | Old yellow enzyme | / | 0.965 | |
| 2h8x | FMN | XenA | / | 0.958 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.953 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.930 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.929 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.928 | |
| 4e2b | FMN | Dehydrogenase | / | 0.923 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.904 | |
| 3l67 | FMN | Xenobiotic reductase | / | 0.897 | |
| 4utm | FNR | Xenobiotic reductase | / | 0.892 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.891 | |
| 3hf3 | FMN | Chromate reductase | / | 0.888 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.888 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.885 | |
| 4rnv | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.879 | |
| 4utl | FNR | Xenobiotic reductase | / | 0.876 | |
| 1gwj | FMN | Morphinone reductase | / | 0.874 | |
| 5cpm | FNR | NADH:flavin oxidoreductase | / | 0.872 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.867 | |
| 3n14 | FMN | Xenobiotic reductase | / | 0.863 | |
| 1z44 | FMN | NADPH dehydrogenase | / | 0.861 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.858 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.856 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.855 | |
| 1z48 | FMN | NADPH dehydrogenase | / | 0.853 | |
| 2hsa | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.849 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.848 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.847 | |
| 4uth | FMN | Xenobiotic reductase | / | 0.845 | |
| 4qnw | FMN | Chanoclavine-I aldehyde reductase easA | / | 0.843 | |
| 3l5l | FMN | Xenobiotic reductase | / | 0.841 | |
| 1z41 | FMN | NADPH dehydrogenase | / | 0.839 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.832 | |
| 2gqa | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.831 | |
| 4utk | FNR | Xenobiotic reductase | / | 0.828 | |
| 4jic | FMN | GTN Reductase | / | 0.820 | |
| 5ebu | FMN | Lactate oxidase | / | 0.812 | |
| 1k02 | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.807 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.806 | |
| 4xq6 | FMN | Dihydroorotate dehydrogenase (quinone) | / | 0.801 | |
| 4bf9 | FMN | tRNA-dihydrouridine(16) synthase | / | 0.798 | |
| 2djl | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.795 | |
| 4yl2 | FMN | Lactate oxidase | / | 0.792 | |
| 2djx | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.788 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.784 | |
| 1vhn | FMN | tRNA-dihydrouridine synthase | / | 0.778 | |
| 3gye | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.767 | |
| 3gr8 | FMN | NADPH dehydrogenase | / | 0.761 | |
| 1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.747 | |
| 1uum | FMN | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.743 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.742 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.741 | |
| 4ef9 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.741 | |
| 2du2 | FMN | Lactate oxidase | / | 0.737 | |
| 3c3n | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.735 | |
| 1jub | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.732 | |
| 3oix | FMN | Dihydroorotate dehydrogenase | / | 0.728 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.724 | |
| 2z6i | FMN | 2-nitropropane dioxygenase | / | 0.723 | |
| 4z9r | FMN | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.717 | |
| 1djq | FMN | Trimethylamine dehydrogenase | 1.5.8.2 | 0.716 | |
| 1h7w | FMN | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.716 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.710 | |
| 1ofd | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.709 | |
| 3kru | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.707 | |
| 4wzh | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.705 | |
| 4yx6 | FMN | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.704 | |
| 2nli | FMN | Lactate oxidase | / | 0.695 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.682 | |
| 1ep3 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.677 | |
| 2e77 | FMN | Lactate oxidase | / | 0.676 | |
| 3vkj | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.673 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.672 | |
| 2qmy | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.671 | |
| 2zrv | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.671 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.670 | |
| 3esz | FMN | Flavodoxin | / | 0.670 | |
| 3w77 | FMN | FMN-dependent NADH-azoreductase | / | 0.669 | |
| 4cw5 | FMN | DfnA | / | 0.669 | |
| 1gox | FMN | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.668 | |
| 4qof | FMN | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.668 | |
| 1kbj | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.666 | |
| 2vyx | FMN | Dodecin | / | 0.665 | |
| 4qoe | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.664 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.662 | |
| 1zwl | FMN | NAD(P)H dehydrogenase (quinone) | 1.6.5.2 | 0.661 | |
| 4yus | FMN | Family 3 adenylate cyclase | / | 0.660 | |
| 2bsl | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.659 | |
| 2zry | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.659 | |
| 1nb9 | RBF | Riboflavin kinase | 2.7.1.26 | 0.658 | |
| 3b05 | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.658 | |
| 4rje | FNR | Lactate oxidase | / | 0.658 | |
| 4x2d | ATP | Fic family protein putative filamentation induced by cAMP protein | / | 0.658 | |
| 2isk | FNR | 5,6-dimethylbenzimidazole synthase | 1.13.11.79 | 0.657 | |
| 3gfz | FMN | Uncharacterized protein | / | 0.657 | |
| 4n65 | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.657 | |
| 1dor | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.656 | |
| 1lm1 | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.656 | |
| 4ees | FMN | Phototropin-2 | 2.7.11.1 | 0.656 | |
| 1ofe | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.655 | |
| 3n39 | FMN | Protein NrdI | / | 0.654 | |
| 3qfr | FMN | NADPH--cytochrome P450 reductase | / | 0.653 | |
| 3gfy | FMN | Uncharacterized protein | / | 0.652 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.652 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.651 | |
| 2isj | FMN | 5,6-dimethylbenzimidazole synthase | 1.13.11.79 | 0.651 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.651 | |
| 1qcw | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.650 |