sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1gra | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 1gra | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.327 | |
| 3grs | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.283 | |
| 3dk9 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.275 | |
| 1k4q | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.263 | |
| 3dk4 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.243 | |
| 4gr1 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.242 | |
| 1ges | FAD | Glutathione reductase | 1.8.1.7 | 1.230 | |
| 1gre | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.230 | |
| 1bwc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.208 | |
| 1grh | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.205 | |
| 2hqm | FAD | Glutathione reductase | 1.8.1.7 | 1.200 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.193 | |
| 1ger | FAD | Glutathione reductase | 1.8.1.7 | 1.191 | |
| 1grb | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.189 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.176 | |
| 1gsn | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.175 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.173 | |
| 1grg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.172 | |
| 1zx9 | FAD | Mercuric reductase | 1.16.1.1 | 1.164 | |
| 3sqp | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.157 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 1.145 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.133 | |
| 1dnc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.108 | |
| 1geu | FAD | Glutathione reductase | 1.8.1.7 | 1.108 | |
| 2eq7 | FAD | Dihydrolipoyl dehydrogenase | / | 1.105 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 1.105 | |
| 2r9z | FAD | Glutathione amide reductase | / | 1.104 | |
| 1get | FAD | Glutathione reductase | 1.8.1.7 | 1.102 | |
| 4kpr | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 1.098 | |
| 1zk7 | FAD | Mercuric reductase | 1.16.1.1 | 1.097 | |
| 2f5z | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 1.073 | |
| 2wba | FAD | Trypanothione reductase | 1.8.1.12 | 1.065 | |
| 1zmd | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 1.061 | |
| 3ean | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 1.052 | |
| 3dgz | FAD | Thioredoxin reductase 2, mitochondrial | 1.8.1.9 | 1.048 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 1.048 | |
| 2eq6 | FAD | Dihydrolipoyl dehydrogenase | / | 1.046 | |
| 2nvk | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 1.042 | |
| 4jdr | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 1.042 | |
| 2v6o | FAD | Thioredoxin glutathione reductase | / | 1.039 | |
| 2tpr | FAD | Trypanothione reductase | 1.8.1.12 | 1.031 | |
| 4j57 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 1.024 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 1.020 | |
| 2rab | FAD | Glutathione amide reductase | / | 1.018 | |
| 2eq9 | FAD | Dihydrolipoyl dehydrogenase | / | 1.013 | |
| 4nev | FAD | Trypanothione reductase | / | 1.013 | |
| 2yqu | FAD | Dihydrolipoyl dehydrogenase | / | 1.011 | |
| 1feb | FAD | Trypanothione reductase | 1.8.1.12 | 1.002 | |
| 2wow | FAD | Trypanothione reductase | / | 0.999 | |
| 2eq8 | FAD | Dihydrolipoyl dehydrogenase | / | 0.998 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.991 | |
| 3dh9 | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.988 | |
| 3rnm | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.984 | |
| 4jq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.982 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.982 | |
| 3dgh | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.978 | |
| 3lad | FAD | Dihydrolipoyl dehydrogenase | / | 0.967 | |
| 2wp5 | FAD | Trypanothione reductase | / | 0.965 | |
| 2cfy | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.959 | |
| 3urh | FAD | Dihydrolipoyl dehydrogenase | / | 0.959 | |
| 2zzc | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.957 | |
| 4j56 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.955 | |
| 1bzl | FAD | Trypanothione reductase | 1.8.1.12 | 0.953 | |
| 4b1b | FAD | Thioredoxin reductase | 1.8.1.9 | 0.943 | |
| 1jeh | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.942 | |
| 2qae | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.941 | |
| 1fec | FAD | Trypanothione reductase | 1.8.1.12 | 0.939 | |
| 1ebd | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.933 | |
| 1zmc | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.915 | |
| 1tyt | FAD | Trypanothione reductase | 1.8.1.12 | 0.910 | |
| 1fea | FAD | Trypanothione reductase | 1.8.1.12 | 0.905 | |
| 2c3c | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.898 | |
| 1gxf | FAD | Trypanothione reductase | 1.8.1.12 | 0.896 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.896 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.891 | |
| 3lzx | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.885 | |
| 2qa1 | FAD | PgaE | / | 0.884 | |
| 3qfb | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.884 | |
| 1nhq | FAD | NADH peroxidase | 1.11.1.1 | 0.883 | |
| 1nhp | FAD | NADH peroxidase | 1.11.1.1 | 0.882 | |
| 2c3d | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.880 | |
| 1lvl | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.876 | |
| 1nhr | FAD | NADH peroxidase | 1.11.1.1 | 0.873 | |
| 5fs8 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.873 | |
| 3lzw | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.871 | |
| 4dna | FAD | Probable glutathione reductase | / | 0.871 | |
| 2j3n | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.870 | |
| 2w0h | FAD | Trypanothione reductase | / | 0.870 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.867 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.866 | |
| 2npx | FAD | NADH peroxidase | 1.11.1.1 | 0.865 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.865 | |
| 1lpf | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.863 | |
| 3nt6 | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.858 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.857 | |
| 1nhs | FAD | NADH peroxidase | 1.11.1.1 | 0.851 | |
| 1npx | FAD | NADH peroxidase | 1.11.1.1 | 0.851 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.848 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.845 | |
| 3cgc | FAD | Coenzyme A disulfide reductase | / | 0.842 | |
| 5buk | FAD | FADH2-dependent halogenase | / | 0.842 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.837 | |
| 1onf | FAD | Glutathione reductase | 1.8.1.7 | 0.837 | |
| 3oz2 | FAD | Digeranylgeranylglycerophospholipid reductase | / | 0.836 | |
| 4cnk | FAD | L-amino acid oxidase | / | 0.834 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.833 | |
| 1mo9 | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.829 | |
| 3icr | FAD | Coenzyme A disulfide reductase | / | 0.829 | |
| 3nta | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.829 | |
| 4m52 | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.829 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.828 | |
| 3ntd | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.827 | |
| 3oc4 | FAD | Oxidoreductase, pyridine nucleotide-disulfide family | / | 0.827 | |
| 3cgd | FAD | Coenzyme A disulfide reductase | / | 0.820 | |
| 3cgb | FAD | Coenzyme A disulfide reductase | / | 0.819 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.818 | |
| 4opd | FDA | Conserved Archaeal protein | / | 0.817 | |
| 5dbj | FAD | FADH2-dependent halogenase PltA | / | 0.817 | |
| 3ics | FAD | Coenzyme A disulfide reductase | / | 0.815 | |
| 3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.813 | |
| 5fs9 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.810 | |
| 1h6v | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.809 | |
| 2a8x | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.809 | |
| 4nte | FAD | DepH | / | 0.807 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.806 | |
| 4j34 | FAD | Kynurenine 3-monooxygenase | / | 0.805 | |
| 4u2t | FAD | Cholesterol oxidase | 1.1.3.6 | 0.804 | |
| 2zbw | FAD | Ferredoxin--NADP reductase | / | 0.803 | |
| 4bjz | FAD | Probable salicylate monooxygenase | / | 0.803 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.803 | |
| 4x4j | FAD | Putative oxygenase | / | 0.802 | |
| 1zy8 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.801 | |
| 4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 0.801 | |
| 2gew | FAD | Cholesterol oxidase | 1.1.3.6 | 0.800 | |
| 3ef6 | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.798 | |
| 4xwr | FAD | Cholesterol oxidase | 1.1.3.6 | 0.797 | |
| 4u2s | FDA | Cholesterol oxidase | 1.1.3.6 | 0.796 | |
| 4opu | FDA | Conserved Archaeal protein | / | 0.795 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.794 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.794 | |
| 1m6i | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.793 | |
| 1n4u | FAE | Cholesterol oxidase | 1.1.3.6 | 0.792 | |
| 5eow | FAD | 6-hydroxynicotinate 3-monooxygenase | 1.14.13.114 | 0.789 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.788 | |
| 3cge | FAD | Coenzyme A disulfide reductase | / | 0.786 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.786 | |
| 4j31 | FAD | Kynurenine 3-monooxygenase | / | 0.785 | |
| 4bk2 | FAD | Probable salicylate monooxygenase | / | 0.784 | |
| 4jn9 | FAD | DepH | / | 0.784 | |
| 3atr | FDA | Conserved Archaeal protein | / | 0.782 | |
| 1n1p | FAD | Cholesterol oxidase | 1.1.3.6 | 0.781 | |
| 3fbs | FAD | Oxidoreductase | / | 0.779 | |
| 4u2l | SFD | Cholesterol oxidase | 1.1.3.6 | 0.778 | |
| 2xdo | FAD | TetX family tetracycline inactivation enzyme | / | 0.776 | |
| 3atq | FDA | Conserved Archaeal protein | / | 0.774 | |
| 4j2w | FAD | Kynurenine 3-monooxygenase | / | 0.774 | |
| 4opt | FDA | Conserved Archaeal protein | / | 0.772 | |
| 4j33 | FAD | Kynurenine 3-monooxygenase | / | 0.771 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.770 | |
| 1gv4 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.769 | |
| 4ntd | FAD | Thioredoxin reductase | / | 0.767 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.765 | |
| 3nix | FAD | Flavoprotein/dehydrogenase | / | 0.762 | |
| 4bv6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.762 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.761 | |
| 4bk3 | FAD | Probable salicylate monooxygenase | / | 0.760 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.758 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.756 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.755 | |
| 4o5q | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.755 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.754 | |
| 4opc | FDA | Conserved Archaeal protein | / | 0.754 | |
| 4mo2 | FDA | UDP-galactopyranose mutase | / | 0.753 | |
| 2gr0 | FAD | Ferredoxin reductase | / | 0.752 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.751 | |
| 4opl | FDA | Conserved Archaeal protein | / | 0.750 | |
| 4tm3 | FAD | KtzI | / | 0.750 | |
| 3ish | FAD | Thioredoxin reductase | 1.8.1.9 | 0.749 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.748 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.747 | |
| 4guu | FA9 | Lysine-specific histone demethylase 1B | 1 | 0.747 | |
| 4nzh | FAD | L-ornithine N(5)-monooxygenase | / | 0.747 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.747 | |
| 5fs6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.747 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.746 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.745 | |
| 4h4z | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.745 | |
| 1i8t | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.744 | |
| 2cul | FAD | GidA-related protein | / | 0.744 | |
| 3all | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.744 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.744 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.744 | |
| 4rsl | FAD | Fructosyl peptide oxidase | / | 0.743 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.742 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.742 | |
| 4lii | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.742 | |
| 4b69 | FAD | L-ornithine N(5)-monooxygenase | / | 0.740 | |
| 4mo2 | FAD | UDP-galactopyranose mutase | / | 0.740 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.738 | |
| 1cc2 | FAD | Cholesterol oxidase | 1.1.3.6 | 0.737 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.737 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.736 | |
| 3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.736 | |
| 3itj | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.736 | |
| 1b8s | FAD | Cholesterol oxidase | 1.1.3.6 | 0.735 | |
| 4tlx | FDA | KtzI | / | 0.735 | |
| 1b4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.733 | |
| 4k5r | FAD | Oxygenase | / | 0.733 | |
| 3axb | FAD | Putative oxidoreductase | / | 0.732 | |
| 1xdi | FAD | NAD(P)H dehydrogenase (quinone) | / | 0.731 | |
| 2bac | FAD | Putative aminooxidase | / | 0.731 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.731 | |
| 4em3 | FAD | Coenzyme A disulfide reductase | / | 0.731 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.731 | |
| 4em4 | FAD | Coenzyme A disulfide reductase | / | 0.730 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.730 | |
| 4b66 | FAD | L-ornithine N(5)-monooxygenase | / | 0.729 | |
| 4h4r | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.729 | |
| 2cdu | FAD | NADH oxidase | / | 0.728 | |
| 4ntc | FAD | Thioredoxin reductase gliT | / | 0.727 | |
| 2gr3 | FAD | Ferredoxin reductase | / | 0.726 | |
| 3mj4 | FAD | UDP-galactopyranose mutase | / | 0.726 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.725 | |
| 4aos | FAD | Steroid monooxygenase | / | 0.725 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.725 | |
| 4cnj | FAD | L-amino acid oxidase | / | 0.724 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.724 | |
| 2yr5 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.723 | |
| 2bab | FAD | Putative aminooxidase | / | 0.722 | |
| 4tm4 | FDA | KtzI | / | 0.722 | |
| 1vdc | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.721 | |
| 1ijh | FAD | Cholesterol oxidase | 1.1.3.6 | 0.720 | |
| 4eqw | FAD | Coenzyme A disulfide reductase | / | 0.720 | |
| 4fx9 | FAD | Coenzyme A disulfide reductase | 1.8.1.14 | 0.720 | |
| 1tdf | FAD | Thioredoxin reductase | 1.8.1.9 | 0.719 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.719 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.719 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.718 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.718 | |
| 1fl2 | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.717 | |
| 2bra | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.717 | |
| 4j36 | FAD | Kynurenine 3-monooxygenase | / | 0.717 | |
| 3gsi | FAD | Dimethylglycine oxidase | 1.5.3.10 | 0.716 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.715 | |
| 2b9x | FAD | Putative aminooxidase | / | 0.715 | |
| 3k30 | ADP | Histamine dehydrogenase | / | 0.715 | |
| 1cbo | FAD | Cholesterol oxidase | 1.1.3.6 | 0.714 | |
| 1k0j | FAD | p-hydroxybenzoate hydroxylase | / | 0.713 | |
| 4eqx | FAD | Coenzyme A disulfide reductase | / | 0.713 | |
| 4tm1 | FDA | KtzI | / | 0.711 | |
| 2bry | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.710 | |
| 4ccq | FAD | Thioredoxin reductase | / | 0.710 | |
| 3ute | FAD | UDP-galactopyranose mutase | / | 0.709 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.708 | |
| 4h4v | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.708 | |
| 1gth | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.706 | |
| 2v3a | FAD | Rubredoxin-NAD(+) reductase | 1.18.1.1 | 0.706 | |
| 2whd | FAD | Thioredoxin reductase | / | 0.706 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.706 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.705 | |
| 2xyo | FAD | TetX family tetracycline inactivation enzyme | / | 0.705 | |
| 4dsg | FAD | Uncharacterized protein | / | 0.704 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.704 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.704 | |
| 1e1m | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.702 | |
| 4h4t | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.702 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.701 | |
| 4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.701 | |
| 4tlz | FAD | KtzI | / | 0.701 | |
| 2cvj | FAD | Thioredoxin reductase related protein | / | 0.700 | |
| 2rgj | FAD | Flavin-containing monooxygenase | / | 0.700 | |
| 2ylr | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.700 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.700 | |
| 5g3t | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.700 | |
| 1n4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.698 | |
| 2bi7 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.697 | |
| 4cbq | FAD | Thioredoxin reductase | / | 0.697 | |
| 5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.697 | |
| 1d7y | FAD | Ferredoxin reductase | / | 0.696 | |
| 1n4w | FAD | Cholesterol oxidase | 1.1.3.6 | 0.696 | |
| 2q0k | FAD | Thioredoxin reductase | 1.8.1.9 | 0.696 | |
| 3vqr | FAD | Putative oxidoreductase | / | 0.696 | |
| 4d04 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.696 | |
| 4h4p | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.696 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.695 | |
| 3gyj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.695 | |
| 2q0l | FAD | Thioredoxin reductase | 1.8.1.9 | 0.694 | |
| 3f8r | NAP | NADH oxidase/thioredoxin reductase | / | 0.694 | |
| 4u8k | FDA | UDP-galactopyranose mutase | / | 0.694 | |
| 3f8p | NAD | NADH oxidase/thioredoxin reductase | / | 0.693 | |
| 4g6g | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.693 | |
| 3cox | FAD | Cholesterol oxidase | 1.1.3.6 | 0.692 | |
| 1djn | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.691 | |
| 3gyi | FAD | Cholesterol oxidase | 1.1.3.6 | 0.691 | |
| 5j60 | FAD | Thioredoxin reductase | / | 0.691 | |
| 3ihg | FAD | Aklavinone 12-hydroxylase RdmE | / | 0.690 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.689 | |
| 2dki | FAD | 3-hydroxybenzoate 4-monooxygenase | 1.14.13.23 | 0.689 | |
| 2eq7 | NAD | Dihydrolipoyl dehydrogenase | / | 0.689 | |
| 4guv | FAD | TetX family tetracycline inactivation enzyme | / | 0.689 | |
| 1yqz | FAD | Coenzyme A disulfide reductase | / | 0.687 | |
| 2jae | FAD | L-amino acid oxidase | / | 0.687 | |
| 4gcm | FAD | Thioredoxin reductase | 1.8.1.9 | 0.687 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.686 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.686 | |
| 2tmd | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.686 | |
| 2ywl | FAD | Thioredoxin reductase related protein | / | 0.686 | |
| 3we0 | FAD | Lysine 2-monooxygenase | / | 0.686 | |
| 2ba9 | FAD | Putative aminooxidase | / | 0.685 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.685 | |
| 4h2n | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.685 | |
| 4xxg | FAD | Cholesterol oxidase | 1.1.3.6 | 0.685 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.684 | |
| 2y48 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.684 | |
| 2yr4 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.684 | |
| 3awi | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | 1.5 | 0.684 | |
| 4ap1 | FAD | Steroid monooxygenase | / | 0.684 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.684 | |
| 5hxw | FAD | L-amino acid deaminase | / | 0.684 | |
| 1d7l | RFL | p-hydroxybenzoate hydroxylase | / | 0.683 | |
| 1f3p | FAD | Ferredoxin reductase | / | 0.683 | |
| 1trb | FAD | Thioredoxin reductase | 1.8.1.9 | 0.683 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.683 | |
| 2b9y | FAD | Putative aminooxidase | / | 0.682 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.682 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.682 | |
| 4g6h | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.682 | |
| 4h4x | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.682 | |
| 1tde | FAD | Thioredoxin reductase | 1.8.1.9 | 0.681 | |
| 2fjb | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.681 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.681 | |
| 3k7t | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.681 | |
| 4u8l | FDA | UDP-galactopyranose mutase | / | 0.681 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.680 | |
| 2q28 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.680 | |
| 1mxt | FAE | Cholesterol oxidase | 1.1.3.6 | 0.679 | |
| 1yy5 | FAD | Polyamine oxidase FMS1 | / | 0.679 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.679 | |
| 2ylw | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.679 | |
| 3f8d | FAD | NADH oxidase/thioredoxin reductase | / | 0.679 | |
| 3qj4 | FAD | Renalase | / | 0.679 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.678 | |
| 2c7g | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.678 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.677 | |
| 4u8p | FDA | UDP-galactopyranose mutase | / | 0.677 | |
| 1q1w | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.676 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.676 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.676 | |
| 3utg | FDA | UDP-galactopyranose mutase | / | 0.676 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.675 | |
| 3cnd | FAD | Polyamine oxidase FMS1 | / | 0.675 | |
| 3l8k | ADP | Dihydrolipoamide dehydrogenase (PdhD-3) | / | 0.675 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.675 | |
| 3uth | FDA | UDP-galactopyranose mutase | / | 0.674 | |
| 4wx1 | FDA | UDP-galactopyranose mutase | / | 0.674 | |
| 1djq | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.673 | |
| 1xpq | FAD | Polyamine oxidase FMS1 | / | 0.673 | |
| 2jb1 | FAD | L-amino acid oxidase | / | 0.673 | |
| 3he3 | FAD | UDP-galactopyranose mutase | / | 0.673 | |
| 3rp8 | FAD | FAD-dependent urate hydroxylase | / | 0.673 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.673 | |
| 3b6d | FAE | Cholesterol oxidase | 1.1.3.6 | 0.672 | |
| 4bur | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.672 | |
| 4c3y | FAD | 3-ketosteroid dehydrogenase | / | 0.672 | |
| 4fwj | FAD | Lysine-specific histone demethylase 1B | 1 | 0.672 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.671 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.671 | |
| 3nyc | FAD | FAD-dependent catabolic D-arginine dehydrogenase DauA | / | 0.670 | |
| 3sm8 | FNK | FAD-dependent catabolic D-arginine dehydrogenase DauA | / | 0.670 | |
| 4gur | FAD | Lysine-specific histone demethylase 1B | 1 | 0.670 | |
| 4h2p | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.670 | |
| 2ji9 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.669 | |
| 2rgo | FAD | Alpha-Glycerophosphate Oxidase | / | 0.669 | |
| 3fmw | FAD | Oxygenase | / | 0.669 | |
| 3q9t | FAY | Uncharacterized protein | / | 0.669 | |
| 4up3 | FAD | Thioredoxin reductase | / | 0.669 | |
| 4ysh | FAD | Glycine oxidase | / | 0.669 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.668 | |
| 4gde | FDA | UDP-galactopyranose mutase | / | 0.668 | |
| 1k0l | FAD | p-hydroxybenzoate hydroxylase | / | 0.667 | |
| 2c4c | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.667 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.667 | |
| 3alj | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.667 | |
| 3gmb | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.667 | |
| 3v76 | FDA | Uncharacterized protein | / | 0.667 | |
| 4z2t | FAD | 2-hydroxybiphenyl-3-monooxygenase | / | 0.665 | |
| 1tdn | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.664 | |
| 1v0j | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.664 | |
| 4ccr | FAD | Thioredoxin reductase | / | 0.664 | |
| 4rpj | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.664 | |
| 1h7w | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.663 | |
| 3ka7 | FAD | Putative oxidoreductase | / | 0.663 | |
| 1jnz | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.662 | |
| 1wam | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.662 | |
| 1y56 | FAD | 382aa long hypothetical sarcosine oxidase | / | 0.662 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.662 | |
| 4a65 | FAD | Thioredoxin reductase | / | 0.662 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.662 | |
| 4b64 | FAD | L-ornithine N(5)-monooxygenase | / | 0.661 | |
| 1ve9 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.659 | |
| 2ylt | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.659 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.659 | |
| 2jib | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.658 | |
| 3fg2 | FAD | Putative rubredoxin reductase | / | 0.658 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.658 | |
| 3ukf | FDA | UDP-galactopyranose mutase | / | 0.658 | |
| 4ap3 | FAD | Steroid monooxygenase | / | 0.658 | |
| 4d7e | FAD | Putative lysine-N-oxygenase | / | 0.658 | |
| 4u8m | FDA | UDP-galactopyranose mutase | / | 0.658 | |
| 1o94 | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.657 | |
| 3m0o | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.657 | |
| 3m12 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.657 | |
| 3m13 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.657 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.656 | |
| 2bi8 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.655 | |
| 4a5l | FAD | Thioredoxin reductase | / | 0.655 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.655 | |
| 4eqs | FAD | Coenzyme A disulfide reductase | / | 0.655 | |
| 4hsu | FAD | Lysine-specific histone demethylase 1B | 1 | 0.655 | |
| 4ylf | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog | / | 0.655 | |
| 2jb2 | FAD | L-amino acid oxidase | / | 0.654 | |
| 3alm | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.654 | |
| 3int | FDA | UDP-galactopyranose mutase | 5.4.99.9 | 0.654 | |
| 5hhf | FDA | UDP-galactopyranose mutase | / | 0.654 | |
| 4emj | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.653 | |
| 4ocg | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.653 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.653 | |
| 3lb8 | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.652 | |
| 4jnq | FDA | Thioredoxin reductase | / | 0.652 | |
| 4h4q | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.651 | |
| 2iid | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.650 | |
| 2ym2 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.650 |