Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1gkc NFH Matrix metalloproteinase-9 3.4.24.35

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1gkc NFHMatrix metalloproteinase-9 3.4.24.35 0.945
1mnc PLHNeutrophil collagenase 3.4.24.34 0.835
2w14 WR2Snake venom metalloproteinase BaP1 3.4.24 0.826
2w13 WR2Snake venom metalloproteinase BaP1 3.4.24 0.814
1rm8 BATMatrix metalloproteinase-16 3.4.24 0.809
2wo8 023Macrophage metalloelastase 3.4.24.65 0.806
2woa 023Macrophage metalloelastase 3.4.24.65 0.798
1jk3 BATMacrophage metalloelastase 3.4.24.65 0.779
3kme INNDisintegrin and metalloproteinase domain-containing protein 17 3.4.24.86 0.769
2dw0 GM6Zinc metalloproteinase-disintegrin-like VAP2B 3.4.24 0.765
2i47 INNDisintegrin and metalloproteinase domain-containing protein 17 3.4.24.86 0.753
3hy7 097A disintegrin and metalloproteinase with thrombospondin motifs 5 3.4.24 0.732
2wo9 023Macrophage metalloelastase 3.4.24.65 0.718
2oy2 ILE_ALA_GLYNeutrophil collagenase 3.4.24.34 0.699
1biw S80Stromelysin-1 3.4.24.17 0.696
2jih 097A disintegrin and metalloproteinase with thrombospondin motifs 1 3.4.24 0.691
4dd8 BATDisintegrin and metalloproteinase domain-containing protein 8 3.4.24 0.689
4gr8 R4CMacrophage metalloelastase 3.4.24.65 0.681
2ovz 5MRMatrix metalloproteinase-9 3.4.24.35 0.678
3l0t INNDisintegrin and metalloproteinase domain-containing protein 17 3.4.24.86 0.675
3tsk QEGMacrophage metalloelastase 3.4.24.65 0.675
1hv5 RXPStromelysin-3 3.4.24 0.672
4gr3 R45Macrophage metalloelastase 3.4.24.65 0.667
3kds NHXATP-dependent zinc metalloprotease FtsH / 0.653