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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1gj4 132 Prothrombin 3.4.21.5

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1gj4 132Prothrombin 3.4.21.5 1.010
1gj5 130Prothrombin 3.4.21.5 0.847
2v3h I25Prothrombin 3.4.21.5 0.792
1o5g CR9Prothrombin 3.4.21.5 0.786
1o2g 696Prothrombin 3.4.21.5 0.767
1c5n ESIProthrombin 3.4.21.5 0.742
1c1u BAIProthrombin 3.4.21.5 0.726
1ghv 120Prothrombin 3.4.21.5 0.718
3plp BBACationic trypsin 3.4.21.4 0.700
1ype UIPProthrombin 3.4.21.5 0.695
2pks G44Prothrombin 3.4.21.5 0.691
4bak M67Prothrombin 3.4.21.5 0.687
2v3o I26Prothrombin 3.4.21.5 0.682
2bok 784Coagulation factor X 3.4.21.6 0.676
1owi 426Urokinase-type plasminogen activator 3.4.21.73 0.674
1c1w BAHProthrombin 3.4.21.5 0.673
2zhq 27UProthrombin 3.4.21.5 0.669
1oyt FSNProthrombin 3.4.21.5 0.664
1vja 7INUrokinase-type plasminogen activator 3.4.21.73 0.664
1wv7 5PICoagulation factor VII 3.4.21.21 0.661
2zp0 PI0Coagulation factor VII 3.4.21.21 0.660
1wtg 3BPCoagulation factor VII 3.4.21.21 0.658
2c4f GILCoagulation factor VII 3.4.21.21 0.650