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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1f92 UKP Urokinase-type plasminogen activator 3.4.21.73

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
1f92 UKPUrokinase-type plasminogen activator 3.4.21.73 1.040
4fud 6UPUrokinase-type plasminogen activator 3.4.21.73 0.769
1owe 675Urokinase-type plasminogen activator 3.4.21.73 0.759
4fub 4UPUrokinase-type plasminogen activator 3.4.21.73 0.749
1u6q 745Urokinase-type plasminogen activator 3.4.21.73 0.746
1owd 497Urokinase-type plasminogen activator 3.4.21.73 0.738
4fue 7UPUrokinase-type plasminogen activator 3.4.21.73 0.736
1owk 303Urokinase-type plasminogen activator 3.4.21.73 0.729
4fui UI3Urokinase-type plasminogen activator 3.4.21.73 0.727
1vja 7INUrokinase-type plasminogen activator 3.4.21.73 0.726
4fuj 1U9Urokinase-type plasminogen activator 3.4.21.73 0.723
3plp BBACationic trypsin 3.4.21.4 0.722
3v0x ANHCationic trypsin 3.4.21.4 0.722
2cf9 348Prothrombin 3.4.21.5 0.719
4bam MM9Prothrombin 3.4.21.5 0.715
4bah MELProthrombin 3.4.21.5 0.711
1k22 MELProthrombin 3.4.21.5 0.705
4fuf 8UPUrokinase-type plasminogen activator 3.4.21.73 0.692
1sqt UI3Urokinase-type plasminogen activator 3.4.21.73 0.691
1ype UIPProthrombin 3.4.21.5 0.689
4bak M67Prothrombin 3.4.21.5 0.688
1lpk CBBCoagulation factor X 3.4.21.6 0.682
2cf8 ESHProthrombin 3.4.21.5 0.682
1wqv PSMCoagulation factor VII 3.4.21.21 0.681
2v3o I26Prothrombin 3.4.21.5 0.681
4bao MVFProthrombin 3.4.21.5 0.681
1riw OSCProthrombin 3.4.21.5 0.680
1w13 SM1Urokinase-type plasminogen activator 3.4.21.73 0.679
4az2 9MUProthrombin 3.4.21.5 0.679
4e7r 0NWProthrombin 3.4.21.5 0.672
4ayy 9MXProthrombin 3.4.21.5 0.671
4ban M6SProthrombin 3.4.21.5 0.671
1wtg 3BPCoagulation factor VII 3.4.21.21 0.670
2a2x NA9Prothrombin 3.4.21.5 0.670
2zhf 49UProthrombin 3.4.21.5 0.670
4ayv 9MQProthrombin 3.4.21.5 0.669
4baq M4ZProthrombin 3.4.21.5 0.666
2zg0 50UProthrombin 3.4.21.5 0.665
2znk 31UProthrombin 3.4.21.5 0.665
1wv7 5PICoagulation factor VII 3.4.21.21 0.664
2zi2 24UProthrombin 3.4.21.5 0.664
1k21 IGNProthrombin 3.4.21.5 0.663
1oyt FSNProthrombin 3.4.21.5 0.663
4ne0 ZZUHydroxylase / 0.663
3utu 1TSProthrombin 3.4.21.5 0.660
4ax9 N5NProthrombin 3.4.21.5 0.659
1vzq SHYProthrombin 3.4.21.5 0.655
2ziq 26UProthrombin 3.4.21.5 0.652