Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1f17 NAI Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1f17 NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.916
1f0y NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.819
3had NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.808
1m76 NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.794
3hdh NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.794
2hdh NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.788
1m75 NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.763
1il0 NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.760
1lso NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.743
1lsj NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.738
4o63 NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.738
3f3s NADLambda-crystallin homolog / 0.730
4kug NAD3-hydroxybutyryl-CoA dehydrogenase / 0.729
1dss NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.721
1vsv NADGlyceraldehyde-3-phosphate dehydrogenase / 0.706
4om8 NAD3-hydroxybutyryl-coA dehydrogenase / 0.706
2vhx NADAlanine dehydrogenase 1.4.1.1 0.702
2vhw NAIAlanine dehydrogenase 1.4.1.1 0.701
2vhz NAIAlanine dehydrogenase 1.4.1.1 0.701
3cps NADGlyceraldehyde-3-phosphate dehydrogenase / 0.699
1dc6 NADGlyceraldehyde-3-phosphate dehydrogenase A / 0.695
1u8f NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.691
2ixb NADAlpha-N-acetylgalactosaminidase 3.2.1.49 0.691
3zw9 NADPeroxisomal bifunctional enzyme 1.1.1.35 0.690
3ikt NADRedox-sensing transcriptional repressor Rex / 0.689
2yy7 NADL-threonine dehydrogenase / 0.688
3ggo NAIPrephenate dehydrogenase / 0.688
3adp NAILambda-crystallin 1.1.1.45 0.687
1lld NADL-lactate dehydrogenase 2 1.1.1.27 0.685
2q3e NAIUDP-glucose 6-dehydrogenase 1.1.1.22 0.683
3x2f NAIAdenosylhomocysteinase / 0.683
4pzd NAD3-Hydroxyacyl-CoA dehydrogenase / 0.683
2dt5 NADRedox-sensing transcriptional repressor Rex / 0.682
3cin NADMyo-inositol-1-phosphate synthase-related protein / 0.682
3wsw NADL-lactate dehydrogenase / 0.682
4nd4 NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase / 0.681
1sc6 NADD-3-phosphoglycerate dehydrogenase 1.1.1.95 0.680
3qv1 NADGlyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic 1.2.1.13 0.679
2vhv NAIAlanine dehydrogenase 1.4.1.1 0.678
2g5c NADPrephenate dehydrogenase / 0.677
3pym NADGlyceraldehyde-3-phosphate dehydrogenase 3 1.2.1.12 0.677
3q2k NAIProbable oxidoreductase / 0.677
2ixa NADAlpha-N-acetylgalactosaminidase 3.2.1.49 0.676
3ggp NADPrephenate dehydrogenase / 0.676
1i2b NADUDP-sulfoquinovose synthase, chloroplastic 3.13.1.1 0.675
5c7o NADGlyceraldehyde-3-phosphate dehydrogenase, testis-specific 1.2.1.12 0.675
4o59 NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.674
1t2c NAIL-lactate dehydrogenase 1.1.1.27 0.673
3m2t NADProbable dehydrogenase / 0.673
1dxy NADD-2-hydroxyisocaproate dehydrogenase 1.1.1 0.672
1uxk NADMalate dehydrogenase / 0.672
4k9d NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.672
1zh8 NAPUncharacterized protein / 0.671
3nt4 NAIInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 1.1.1.18 0.671
3zcx NADGlyceraldehyde-3-phosphate dehydrogenase / 0.671
1hdg NADGlyceraldehyde-3-phosphate dehydrogenase / 0.670
3cmc NADGlyceraldehyde-3-phosphate dehydrogenase / 0.670
3nt2 NADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 1.1.1.18 0.670
3oet NADErythronate-4-phosphate dehydrogenase / 0.670
1gd1 NADGlyceraldehyde-3-phosphate dehydrogenase / 0.669
3zdf NADGlyceraldehyde-3-phosphate dehydrogenase / 0.669
1szj NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.668
3v1y NADGlyceraldehyde-3-phosphate dehydrogenase 1, cytosolic 1.2.1.12 0.668
3hja NADGlyceraldehyde-3-phosphate dehydrogenase / 0.666
3keo NADRedox-sensing transcriptional repressor Rex / 0.666
4xgi NADGlutamate dehydrogenase / 0.666
2pa3 NAID-3-phosphoglycerate dehydrogenase 1.1.1.95 0.665
3b1j NADGlyceraldehyde-3-phosphate dehydrogenase / 0.665
4p8r NADGlyceraldehyde-3-phosphate dehydrogenase / 0.665
3d4p NADL-lactate dehydrogenase 1 1.1.1.27 0.664
4nd2 A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase / 0.664
1gv0 NADMalate dehydrogenase / 0.663
2hjr APRMalate dehydrogenase, adjacent gene encodes predicted lactate dehydrogenase / 0.663
2rcy NAPPyrroline-5-carboxylate reductase / 0.662
3dmt NADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal 1.2.1.12 0.662
3pqf NADL-lactate dehydrogenase 1.1.1.27 0.662
3uko NADAlcohol dehydrogenase class-3 / 0.662
4z0h NADGlyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic 1.2.1.12 0.662
1gad NADGlyceraldehyde-3-phosphate dehydrogenase A / 0.661
2vyv NADGlyceraldehyde-3-phosphate dehydrogenase A / 0.661
2dfv NADL-threonine 3-dehydrogenase / 0.660
3doc NADGlyceraldehyde-3-phosphate dehydrogenase / 0.660
4yr9 NADL-threonine 3-dehydrogenase, mitochondrial 1.1.1.103 0.660
1mp0 NADAlcohol dehydrogenase class-3 1.1.1.1 0.659
2dvm NAD439aa long hypothetical malate oxidoreductase (NAD) [malic enzyme] / 0.659
1pl8 NADSorbitol dehydrogenase 1.1.1.14 0.658
2g82 NADGlyceraldehyde-3-phosphate dehydrogenase / 0.658
3k2b NADGlyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic 1.2.1.13 0.658
3pef NAPGlyoxalate/3-oxopropanoate/4-oxobutanoate reductase / 0.658
4ng5 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.658
2x0i NAIMalate dehydrogenase / 0.657
3ggg NADPrephenate dehydrogenase / 0.657
1cer NADGlyceraldehyde-3-phosphate dehydrogenase / 0.656
1j0x NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.656
1nq5 NADGlyceraldehyde-3-phosphate dehydrogenase / 0.656
4nfs NAJAlcohol dehydrogenase E chain 1.1.1.1 0.656
2fn7 NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase / 0.655
3dbv NADGlyceraldehyde-3-phosphate dehydrogenase / 0.655
4lsm NADGlyceraldehyde-3-phosphate dehydrogenase / 0.655
1e1k FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.654
3cif NADGlyceraldehyde-3-phosphate dehydrogenase / 0.654
1e1m FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.653
1guy NADMalate dehydrogenase / 0.653
1nqo NADGlyceraldehyde-3-phosphate dehydrogenase / 0.653
3gvi ADPMalate dehydrogenase / 0.653
2qg4 NADUDP-glucose 6-dehydrogenase 1.1.1.22 0.652
4hb9 FADUncharacterized protein / 0.652
1o0s NAINAD-dependent malic enzyme, mitochondrial 1.1.1.38 0.651
4j4b NAIUncharacterized protein / 0.651
1bw9 NADPhenylalanine dehydrogenase / 0.650
1gae NADGlyceraldehyde-3-phosphate dehydrogenase A / 0.650