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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1exa 394 Retinoic acid receptor gamma

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1exa 394Retinoic acid receptor gamma / 1.429
1fd0 254Retinoic acid receptor gamma / 0.858
1fcx 184Retinoic acid receptor gamma / 0.833
1fcy 564Retinoic acid receptor gamma / 0.799
4dm8 REARetinoic acid receptor beta / 0.750
2lbd REARetinoic acid receptor gamma / 0.727
4dm6 TTBRetinoic acid receptor beta / 0.698
1mzn BM6Retinoic acid receptor RXR-alpha / 0.685
1mvc BM6Retinoic acid receptor RXR-alpha / 0.674
4fv9 E71Mitogen-activated protein kinase 1 2.7.11.24 0.656
3vt4 5YIVitamin D3 receptor / 0.654