sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1dnc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 1dnc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.255 | |
| 1gre | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.212 | |
| 1gsn | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.212 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.187 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.177 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.176 | |
| 1grb | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.175 | |
| 3dk4 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.162 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.160 | |
| 1grg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.114 | |
| 1grh | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.113 | |
| 1gra | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.108 | |
| 3dk9 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.090 | |
| 1bwc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.089 | |
| 3grs | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.085 | |
| 1zx9 | FAD | Mercuric reductase | 1.16.1.1 | 1.075 | |
| 1k4q | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.069 | |
| 4gr1 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.063 | |
| 1get | FAD | Glutathione reductase | 1.8.1.7 | 1.059 | |
| 3dh9 | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 1.048 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 1.028 | |
| 1zk7 | FAD | Mercuric reductase | 1.16.1.1 | 1.011 | |
| 1ger | FAD | Glutathione reductase | 1.8.1.7 | 1.009 | |
| 2nvk | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.999 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.993 | |
| 2hqm | FAD | Glutathione reductase | 1.8.1.7 | 0.986 | |
| 1geu | FAD | Glutathione reductase | 1.8.1.7 | 0.980 | |
| 1ges | FAD | Glutathione reductase | 1.8.1.7 | 0.974 | |
| 3sqp | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.974 | |
| 3lzw | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.933 | |
| 3lzx | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.928 | |
| 4kpr | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.928 | |
| 1npx | FAD | NADH peroxidase | 1.11.1.1 | 0.920 | |
| 3dgh | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.920 | |
| 1zmd | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.916 | |
| 1nhq | FAD | NADH peroxidase | 1.11.1.1 | 0.908 | |
| 2npx | FAD | NADH peroxidase | 1.11.1.1 | 0.908 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.908 | |
| 1nhs | FAD | NADH peroxidase | 1.11.1.1 | 0.905 | |
| 1nhr | FAD | NADH peroxidase | 1.11.1.1 | 0.904 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.897 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.893 | |
| 1nhp | FAD | NADH peroxidase | 1.11.1.1 | 0.890 | |
| 3atq | FDA | Conserved Archaeal protein | / | 0.890 | |
| 4opd | FDA | Conserved Archaeal protein | / | 0.885 | |
| 3dgz | FAD | Thioredoxin reductase 2, mitochondrial | 1.8.1.9 | 0.877 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.877 | |
| 2zzc | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.876 | |
| 3lad | FAD | Dihydrolipoyl dehydrogenase | / | 0.876 | |
| 4j57 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.872 | |
| 2wow | FAD | Trypanothione reductase | / | 0.868 | |
| 1feb | FAD | Trypanothione reductase | 1.8.1.12 | 0.862 | |
| 3atr | FDA | Conserved Archaeal protein | / | 0.861 | |
| 2v6o | FAD | Thioredoxin glutathione reductase | / | 0.860 | |
| 2rab | FAD | Glutathione amide reductase | / | 0.859 | |
| 4opt | FDA | Conserved Archaeal protein | / | 0.854 | |
| 3ean | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.853 | |
| 3nta | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.852 | |
| 2wba | FAD | Trypanothione reductase | 1.8.1.12 | 0.850 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.850 | |
| 2eq6 | FAD | Dihydrolipoyl dehydrogenase | / | 0.849 | |
| 2eq8 | FAD | Dihydrolipoyl dehydrogenase | / | 0.847 | |
| 4opc | FDA | Conserved Archaeal protein | / | 0.847 | |
| 2c3c | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.846 | |
| 4b1b | FAD | Thioredoxin reductase | 1.8.1.9 | 0.845 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.843 | |
| 1fec | FAD | Trypanothione reductase | 1.8.1.12 | 0.842 | |
| 3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.840 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.839 | |
| 2zbw | FAD | Ferredoxin--NADP reductase | / | 0.839 | |
| 1mo9 | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.837 | |
| 2qa1 | FAD | PgaE | / | 0.834 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.832 | |
| 4gcm | FAD | Thioredoxin reductase | 1.8.1.9 | 0.829 | |
| 1gxf | FAD | Trypanothione reductase | 1.8.1.12 | 0.826 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.826 | |
| 4bjz | FAD | Probable salicylate monooxygenase | / | 0.826 | |
| 2eq7 | FAD | Dihydrolipoyl dehydrogenase | / | 0.825 | |
| 4bk3 | FAD | Probable salicylate monooxygenase | / | 0.825 | |
| 2r9z | FAD | Glutathione amide reductase | / | 0.824 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.822 | |
| 4jdr | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.819 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.818 | |
| 4nev | FAD | Trypanothione reductase | / | 0.818 | |
| 1tde | FAD | Thioredoxin reductase | 1.8.1.9 | 0.817 | |
| 4j34 | FAD | Kynurenine 3-monooxygenase | / | 0.816 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.815 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.815 | |
| 5fs8 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.813 | |
| 3rnm | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.810 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.808 | |
| 3oz2 | FAD | Digeranylgeranylglycerophospholipid reductase | / | 0.804 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.801 | |
| 1onf | FAD | Glutathione reductase | 1.8.1.7 | 0.800 | |
| 2wp5 | FAD | Trypanothione reductase | / | 0.799 | |
| 4jq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.799 | |
| 4bk2 | FAD | Probable salicylate monooxygenase | / | 0.797 | |
| 4rsl | FAD | Fructosyl peptide oxidase | / | 0.796 | |
| 2c3d | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.795 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.795 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.795 | |
| 3ka7 | FAD | Putative oxidoreductase | / | 0.795 | |
| 1fea | FAD | Trypanothione reductase | 1.8.1.12 | 0.792 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.792 | |
| 1m6i | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.791 | |
| 2cfy | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.791 | |
| 2qae | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.791 | |
| 3fbs | FAD | Oxidoreductase | / | 0.791 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.791 | |
| 1bzl | FAD | Trypanothione reductase | 1.8.1.12 | 0.789 | |
| 3ish | FAD | Thioredoxin reductase | 1.8.1.9 | 0.789 | |
| 3cge | FAD | Coenzyme A disulfide reductase | / | 0.787 | |
| 3oc4 | FAD | Oxidoreductase, pyridine nucleotide-disulfide family | / | 0.787 | |
| 4j33 | FAD | Kynurenine 3-monooxygenase | / | 0.786 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.785 | |
| 2f5z | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.784 | |
| 2eq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.783 | |
| 4j36 | FAD | Kynurenine 3-monooxygenase | / | 0.782 | |
| 2tpr | FAD | Trypanothione reductase | 1.8.1.12 | 0.781 | |
| 1i8t | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.780 | |
| 3ef6 | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.779 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.777 | |
| 1lpf | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.776 | |
| 2yqu | FAD | Dihydrolipoyl dehydrogenase | / | 0.776 | |
| 3alj | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.776 | |
| 2yr4 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.775 | |
| 3f8d | FAD | NADH oxidase/thioredoxin reductase | / | 0.774 | |
| 4opu | FDA | Conserved Archaeal protein | / | 0.774 | |
| 4u2t | FAD | Cholesterol oxidase | 1.1.3.6 | 0.774 | |
| 4x4j | FAD | Putative oxygenase | / | 0.774 | |
| 4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.771 | |
| 3cgd | FAD | Coenzyme A disulfide reductase | / | 0.770 | |
| 4bv6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.770 | |
| 4ocg | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.770 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.770 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.770 | |
| 3m13 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.769 | |
| 4nte | FAD | DepH | / | 0.766 | |
| 1b4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.763 | |
| 3qfb | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.763 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.761 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.759 | |
| 2bi7 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.759 | |
| 2j3n | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.759 | |
| 4d04 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.759 | |
| 3kve | FAD | L-amino-acid oxidase | / | 0.758 | |
| 3ics | FAD | Coenzyme A disulfide reductase | / | 0.757 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.756 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.755 | |
| 4emj | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.755 | |
| 2v3a | FAD | Rubredoxin-NAD(+) reductase | 1.18.1.1 | 0.754 | |
| 3axb | FAD | Putative oxidoreductase | / | 0.754 | |
| 4j2w | FAD | Kynurenine 3-monooxygenase | / | 0.754 | |
| 4j31 | FAD | Kynurenine 3-monooxygenase | / | 0.754 | |
| 3b6d | FAE | Cholesterol oxidase | 1.1.3.6 | 0.753 | |
| 4h4z | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.753 | |
| 4udq | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.753 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.752 | |
| 3we0 | FAD | Lysine 2-monooxygenase | / | 0.752 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.751 | |
| 1f8s | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.749 | |
| 4lii | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.749 | |
| 4j56 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.748 | |
| 4tm1 | FDA | KtzI | / | 0.748 | |
| 5fs9 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.748 | |
| 1fl2 | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.747 | |
| 2w0h | FAD | Trypanothione reductase | / | 0.747 | |
| 5hxw | FAD | L-amino acid deaminase | / | 0.747 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.746 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.746 | |
| 4k5r | FAD | Oxygenase | / | 0.746 | |
| 4ntc | FAD | Thioredoxin reductase gliT | / | 0.746 | |
| 4eqw | FAD | Coenzyme A disulfide reductase | / | 0.744 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.743 | |
| 2tmd | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.743 | |
| 3alm | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.743 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.742 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.742 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.742 | |
| 4cnk | FAD | L-amino acid oxidase | / | 0.742 | |
| 4mo2 | FDA | UDP-galactopyranose mutase | / | 0.741 | |
| 1f8r | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.740 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.740 | |
| 1ps9 | FAD | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.740 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.740 | |
| 4em3 | FAD | Coenzyme A disulfide reductase | / | 0.740 | |
| 1tdf | FAD | Thioredoxin reductase | 1.8.1.9 | 0.739 | |
| 3rp8 | FAD | FAD-dependent urate hydroxylase | / | 0.738 | |
| 4em4 | FAD | Coenzyme A disulfide reductase | / | 0.738 | |
| 4eqs | FAD | Coenzyme A disulfide reductase | / | 0.738 | |
| 4mo2 | FAD | UDP-galactopyranose mutase | / | 0.738 | |
| 1jnz | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.736 | |
| 1yqz | FAD | Coenzyme A disulfide reductase | / | 0.735 | |
| 4eqr | FAD | Coenzyme A disulfide reductase | / | 0.735 | |
| 3uox | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.734 | |
| 4c3x | FAD | 3-ketosteroid dehydrogenase | / | 0.734 | |
| 4h4x | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.733 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.732 | |
| 1d7y | FAD | Ferredoxin reductase | / | 0.731 | |
| 2rgj | FAD | Flavin-containing monooxygenase | / | 0.731 | |
| 4dna | FAD | Probable glutathione reductase | / | 0.731 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.729 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.729 | |
| 1zmc | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.728 | |
| 3cnt | FAD | Polyamine oxidase FMS1 | / | 0.728 | |
| 3he3 | FAD | UDP-galactopyranose mutase | / | 0.728 | |
| 4b66 | FAD | L-ornithine N(5)-monooxygenase | / | 0.728 | |
| 2gv8 | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.727 | |
| 5fs6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.727 | |
| 4bur | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.726 | |
| 1n4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.725 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.725 | |
| 3all | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.725 | |
| 4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 0.725 | |
| 2iid | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.724 | |
| 5eow | FAD | 6-hydroxynicotinate 3-monooxygenase | 1.14.13.114 | 0.724 | |
| 4h4v | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.723 | |
| 4jy2 | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.723 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.723 | |
| 4uir | FAD | Oleate hydratase | 4.2.1.53 | 0.723 | |
| 5i39 | FAD | L-amino acid deaminase | / | 0.723 | |
| 3mj4 | FAD | UDP-galactopyranose mutase | / | 0.722 | |
| 2fjb | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.721 | |
| 3ept | FDA | Putative FAD-monooxygenase | / | 0.721 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.721 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.721 | |
| 1gv4 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.720 | |
| 1tdn | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.720 | |
| 4g6g | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.720 | |
| 4u2s | FDA | Cholesterol oxidase | 1.1.3.6 | 0.720 | |
| 4xwz | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.720 | |
| 1k0j | FAD | p-hydroxybenzoate hydroxylase | / | 0.719 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.719 | |
| 4h2p | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.719 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.718 | |
| 4b69 | FAD | L-ornithine N(5)-monooxygenase | / | 0.718 | |
| 4c3y | FAD | 3-ketosteroid dehydrogenase | / | 0.718 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.717 | |
| 1tdk | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.717 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.717 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.716 | |
| 3k30 | ADP | Histamine dehydrogenase | / | 0.716 | |
| 3urh | FAD | Dihydrolipoyl dehydrogenase | / | 0.716 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.715 | |
| 4tm4 | FDA | KtzI | / | 0.715 | |
| 2y48 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.714 | |
| 3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.714 | |
| 2bry | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.713 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.713 | |
| 4nzh | FAD | L-ornithine N(5)-monooxygenase | / | 0.713 | |
| 4tlz | FAD | KtzI | / | 0.713 | |
| 2xdo | FAD | TetX family tetracycline inactivation enzyme | / | 0.712 | |
| 3jsk | AHZ | Thiamine thiazole synthase | / | 0.712 | |
| 3ntd | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.712 | |
| 4ccq | FAD | Thioredoxin reductase | / | 0.712 | |
| 4h4t | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.712 | |
| 1djn | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.711 | |
| 1ng3 | FAD | Glycine oxidase | 1.4.3.19 | 0.711 | |
| 4ykf | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.711 | |
| 4icy | FAD | PgaE | / | 0.710 | |
| 4b63 | FAD | L-ornithine N(5)-monooxygenase | / | 0.709 | |
| 4eqx | FAD | Coenzyme A disulfide reductase | / | 0.709 | |
| 4o5u | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.709 | |
| 1b8s | FAD | Cholesterol oxidase | 1.1.3.6 | 0.707 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.707 | |
| 3cox | FAD | Cholesterol oxidase | 1.1.3.6 | 0.707 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.707 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.706 | |
| 1cc2 | FAD | Cholesterol oxidase | 1.1.3.6 | 0.705 | |
| 1ebd | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.705 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.705 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.705 | |
| 1jeh | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.704 | |
| 2c4c | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.704 | |
| 2gr0 | FAD | Ferredoxin reductase | / | 0.704 | |
| 3gmb | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.704 | |
| 3l8k | ADP | Dihydrolipoamide dehydrogenase (PdhD-3) | / | 0.704 | |
| 4jnq | FDA | Thioredoxin reductase | / | 0.704 | |
| 1tdo | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.703 | |
| 3lxd | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.703 | |
| 5g3t | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.703 | |
| 3nix | FAD | Flavoprotein/dehydrogenase | / | 0.702 | |
| 4m52 | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.702 | |
| 1ijh | FAD | Cholesterol oxidase | 1.1.3.6 | 0.701 | |
| 1h7w | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.699 | |
| 4fx9 | FAD | Coenzyme A disulfide reductase | 1.8.1.14 | 0.699 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.699 | |
| 4yjd | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.699 | |
| 2bac | FAD | Putative aminooxidase | / | 0.698 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.698 | |
| 3f8r | NAP | NADH oxidase/thioredoxin reductase | / | 0.698 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.698 | |
| 4up3 | FAD | Thioredoxin reductase | / | 0.698 | |
| 1q1w | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.697 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.697 | |
| 3ukk | FAD | UDP-galactopyranose mutase | / | 0.697 | |
| 4u8m | FDA | UDP-galactopyranose mutase | / | 0.697 | |
| 4guu | FA9 | Lysine-specific histone demethylase 1B | 1 | 0.696 | |
| 1gte | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.695 | |
| 2gmj | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.695 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.695 | |
| 3lb8 | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.695 | |
| 4cbq | FAD | Thioredoxin reductase | / | 0.695 | |
| 4gde | FDA | UDP-galactopyranose mutase | / | 0.695 | |
| 1djq | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.694 | |
| 2gew | FAD | Cholesterol oxidase | 1.1.3.6 | 0.694 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.694 | |
| 2jib | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.694 | |
| 3vqr | FAD | Putative oxidoreductase | / | 0.694 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.693 | |
| 3qj4 | FAD | Renalase | / | 0.693 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.692 | |
| 2eq7 | NAD | Dihydrolipoyl dehydrogenase | / | 0.692 | |
| 2q0l | FAD | Thioredoxin reductase | 1.8.1.9 | 0.692 | |
| 3m12 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.692 | |
| 4txi | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.692 | |
| 1vdc | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.691 | |
| 2jb1 | FAD | L-amino acid oxidase | / | 0.691 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.690 | |
| 1lvl | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.690 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.690 | |
| 4u8i | FDA | UDP-galactopyranose mutase | / | 0.690 | |
| 1o94 | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.689 | |
| 3icr | FAD | Coenzyme A disulfide reductase | / | 0.689 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.689 | |
| 2gr3 | FAD | Ferredoxin reductase | / | 0.688 | |
| 2q0k | FAD | Thioredoxin reductase | 1.8.1.9 | 0.688 | |
| 3int | FDA | UDP-galactopyranose mutase | 5.4.99.9 | 0.688 | |
| 4emw | FAD | Coenzyme A disulfide reductase | / | 0.688 | |
| 4h4p | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.688 | |
| 1k0l | FAD | p-hydroxybenzoate hydroxylase | / | 0.687 | |
| 1tyt | FAD | Trypanothione reductase | 1.8.1.12 | 0.687 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.687 | |
| 3utg | FDA | UDP-galactopyranose mutase | / | 0.687 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.687 | |
| 1d7l | RFL | p-hydroxybenzoate hydroxylase | / | 0.686 | |
| 4b64 | FAD | L-ornithine N(5)-monooxygenase | / | 0.686 | |
| 4u8k | FDA | UDP-galactopyranose mutase | / | 0.686 | |
| 1y56 | ATP | Uncharacterized protein | / | 0.685 | |
| 3v76 | FDA | Uncharacterized protein | / | 0.685 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.684 | |
| 4a65 | FAD | Thioredoxin reductase | / | 0.684 | |
| 4i58 | FAD | Cyclohexylamine Oxidase | / | 0.684 | |
| 4tlx | FDA | KtzI | / | 0.684 | |
| 1h83 | FAD | Polyamine oxidase | 1.5.3.14 | 0.683 | |
| 4wx1 | FDA | UDP-galactopyranose mutase | / | 0.683 | |
| 1reo | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.682 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.682 | |
| 3gyi | FAD | Cholesterol oxidase | 1.1.3.6 | 0.682 | |
| 4jn9 | FAD | DepH | / | 0.682 | |
| 4z2t | FAD | 2-hydroxybiphenyl-3-monooxygenase | / | 0.682 | |
| 1c0l | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.681 | |
| 1ng4 | FAD | Glycine oxidase | 1.4.3.19 | 0.681 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.681 | |
| 2vq7 | FAD | Putative flavin-containing monooxygenase | / | 0.681 | |
| 4ccr | FAD | Thioredoxin reductase | / | 0.681 | |
| 4d7e | FAD | Putative lysine-N-oxygenase | / | 0.681 | |
| 4hc4 | SAH | Protein arginine N-methyltransferase 6 | / | 0.681 | |
| 1trb | FAD | Thioredoxin reductase | 1.8.1.9 | 0.680 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.680 | |
| 2bi8 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.679 | |
| 2du8 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.679 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.679 | |
| 3f8p | NAD | NADH oxidase/thioredoxin reductase | / | 0.679 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.678 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.678 | |
| 2cdu | ADP | NADH oxidase | / | 0.678 | |
| 1mxt | FAE | Cholesterol oxidase | 1.1.3.6 | 0.677 | |
| 1n1p | FAD | Cholesterol oxidase | 1.1.3.6 | 0.677 | |
| 1n4w | FAD | Cholesterol oxidase | 1.1.3.6 | 0.677 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.677 | |
| 3awi | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | 1.5 | 0.677 | |
| 4xwr | FAD | Cholesterol oxidase | 1.1.3.6 | 0.677 | |
| 4xxg | FAD | Cholesterol oxidase | 1.1.3.6 | 0.677 | |
| 5j60 | FAD | Thioredoxin reductase | / | 0.677 | |
| 4o5q | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.676 | |
| 4usr | FAD | Monooxygenase | / | 0.676 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.675 | |
| 4tm0 | FAD | KtzI | / | 0.675 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.674 | |
| 3uth | FDA | UDP-galactopyranose mutase | / | 0.674 | |
| 5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.674 | |
| 2bab | FAD | Putative aminooxidase | / | 0.673 | |
| 3itj | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.673 | |
| 1e1m | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.672 | |
| 4h4r | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.672 | |
| 1h6v | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.671 | |
| 2c7g | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.671 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.671 | |
| 2gqf | FAD | Uncharacterized protein HI_0933 | / | 0.670 | |
| 1c0k | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.669 | |
| 2yg6 | FAD | Putrescine oxidase | / | 0.669 | |
| 3kyb | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.669 | |
| 4u8j | FDA | UDP-galactopyranose mutase | / | 0.669 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.668 | |
| 4b67 | FAD | L-ornithine N(5)-monooxygenase | / | 0.668 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.667 | |
| 1v0j | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.667 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.667 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.667 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.667 | |
| 4c5o | FAD | Putative monooxygenase | / | 0.667 | |
| 1wam | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.666 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.666 | |
| 3fmw | FAD | Oxygenase | / | 0.666 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.666 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.666 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.666 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.666 | |
| 3q9t | FAY | Uncharacterized protein | / | 0.665 | |
| 3ukf | FDA | UDP-galactopyranose mutase | / | 0.665 | |
| 3fg2 | FAD | Putative rubredoxin reductase | / | 0.664 | |
| 3lov | FAD | Protoporphyrinogen oxidase | / | 0.664 | |
| 4u8o | FDA | UDP-galactopyranose mutase | / | 0.664 | |
| 4u8p | FDA | UDP-galactopyranose mutase | / | 0.664 | |
| 5dbj | FAD | FADH2-dependent halogenase PltA | / | 0.664 | |
| 1e1l | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.663 | |
| 2jae | FAD | L-amino acid oxidase | / | 0.663 | |
| 3m0o | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.663 | |
| 1knr | FAD | L-aspartate oxidase | 1.4.3.16 | 0.662 | |
| 3hdy | FAD | UDP-galactopyranose mutase | / | 0.662 | |
| 2cdu | FAD | NADH oxidase | / | 0.661 | |
| 2cul | FAD | GidA-related protein | / | 0.661 | |
| 3gd3 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.661 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.661 | |
| 1kf6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.660 | |
| 2bra | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.660 | |
| 2vqb | FAD | Putative flavin-containing monooxygenase | / | 0.660 | |
| 2xyo | FAD | TetX family tetracycline inactivation enzyme | / | 0.660 | |
| 2yr5 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.660 | |
| 3gsi | FAD | Dimethylglycine oxidase | 1.5.3.10 | 0.660 | |
| 4gur | FAD | Lysine-specific histone demethylase 1B | 1 | 0.660 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.660 | |
| 1cbo | FAD | Cholesterol oxidase | 1.1.3.6 | 0.659 | |
| 2dki | FAD | 3-hydroxybenzoate 4-monooxygenase | 1.14.13.23 | 0.659 | |
| 3sgl | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.659 | |
| 4u8l | FDA | UDP-galactopyranose mutase | / | 0.659 | |
| 4u8n | FDA | UDP-galactopyranose mutase | / | 0.659 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.659 | |
| 2q28 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.658 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.658 | |
| 3utf | FDA | UDP-galactopyranose mutase | / | 0.657 | |
| 4aox | FAD | Steroid monooxygenase | / | 0.657 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.657 | |
| 1n4u | FAE | Cholesterol oxidase | 1.1.3.6 | 0.656 | |
| 5buk | FAD | FADH2-dependent halogenase | / | 0.656 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.656 | |
| 1v59 | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.655 | |
| 2c31 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.655 | |
| 3gwd | FAD | Cyclohexanone monooxygenase | / | 0.655 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.655 | |
| 2ji7 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.654 | |
| 3grr | SAH | Probable ribosomal RNA small subunit methyltransferase A | / | 0.654 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.654 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.654 | |
| 2ji6 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.653 | |
| 2zth | SAM | Catechol O-methyltransferase | 2.1.1.6 | 0.653 | |
| 3p9u | FAD | TetX family tetracycline inactivation enzyme | / | 0.653 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.653 | |
| 2cvj | FAD | Thioredoxin reductase related protein | / | 0.652 | |
| 4nwz | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.652 | |
| 2yvf | FAD | Ferredoxin reductase | / | 0.651 | |
| 3aeb | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.651 | |
| 4ysh | FAD | Glycine oxidase | / | 0.651 | |
| 3a27 | SAM | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.650 | |
| 3ihg | FAD | Aklavinone 12-hydroxylase RdmE | / | 0.650 | |
| 4h4q | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.650 |