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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1ah3 TOL Aldose reductase 1.1.1.21

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1ah3 TOLAldose reductase 1.1.1.21 1.148
2fzb TOLAldose reductase 1.1.1.21 0.901
2pdl TOLAldose reductase 1.1.1.21 0.884
1zua TOLAldo-keto reductase family 1 member B10 1.1.1 0.856
2fzd TOLAldose reductase 1.1.1.21 0.789
2duz ZSTAldose reductase 1.1.1.21 0.711
2ikj 393Aldose reductase 1.1.1.21 0.671
3ld5 LDTAldose reductase 1.1.1.21 0.653